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Autophagy
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DNA Damage
Epigenetics
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MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Name Index A
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Name Index A
AZD4205
(Catalog# : 20178710, Cas# :
2091134-35-7
)
AZD4205 is a highly potent JAK1-selective kinase inhibitor with excellent preclinical
ACY-775
(Catalog# : 77821, Cas# :
1375466-18-4
)
ACY-775 is a potent and selective HDAC6 inhbiitor. ACY-775 inhibits HDAC6 with low na
AAI-101
(Catalog# : 1773101, Cas# :
1001404-83-6
)
AAI101(AAI-101) is a novel extended-spectrum -lactamase inhibitor.The combination of
AV-412 Tosylate
(Catalog# : 17030105, Cas# :
451493-31-5
)
AV-412, also known as MP-412, is a second-generation, orally bioavailable dual kinase
AZD-7594
(Catalog# : 17022812, Cas# :
1196509-60-0
)
AZD-7594, also known as AZ13189620, is an inhaled selective glucocorticoid receptor (
AZD3839
(Catalog# : 17022710, Cas# :
1227163-56-5
)
AZD3839 is a potent and selective BACE1 inhibitor. AZD3839 is clinical candidate for
A-1210477
(Catalog# : 17022404, Cas# :
1668553-26-1
)
A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 induces the hallmarks
Apatinib
(Catalog# : 17022301, Cas# :
811803-05-1
)
Apatinib is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM.
Amikacin sulfate
(Catalog# : 17021407, Cas# :
39831-55-5
)
Amikacin sulfate(BAY416651 sulfate) is a semi-synthetic aminoglycoside antibiotic der
AFN-1252
(Catalog# : 17021406, Cas# :
620175-39-5
)
AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (F
AZD3293 (LY3314814)
(Catalog# : 17021318, Cas# :
1383982-64-6
)
AZD3293, also known as LY3314814 is an oral beta-secretase 1 cleaving enzyme (BACE)
APR-246 (PRIMA-1MET)
(Catalog# : 17021316, Cas# :
5291-32-7
)
APR-246, also known as PRIMA-1MET, is a small organic molecule that has been shown to
AZD-8835
(Catalog# : 102703, Cas# :
1620576-64-8
)
AZD8835 is a potent and selective inhibitor of PI3Kalpha and PI3Kdelata with excellen
AZD6482 (S-isomer)
(Catalog# : 17011901, Cas# :
1173900-37-2
)
AZD6482 is a potent, selective and ATP competitive PI3K inhibitor (IC(50) 0.01 μm).
7ACC2
(Catalog# : 17011302, Cas# :
1472624-85-3
)
7ACC2 is a potent MCT inhibitor. Monocarboxylate transporters (MCTs) catalyze the pro
AZD-5597
(Catalog# : 16122865, Cas# :
924641-59-8
)
AZD-5597 is potent CDK inhibitor with in vitro anti-proliferative effects against a r
AZD-5069
(Catalog# : 16122864, Cas# :
878385-84-3
)
AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neu
AZD-2461
(Catalog# : 16122863, Cas# :
1174043-16-3
)
AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. A
Avitinib maleate
(Catalog# : 16122862, Cas# :
1557268-88-8
)
Avitinib is an orally available, irreversible, epidermal growth factor receptor (EGFR
Avibactam sodium
(Catalog# : 16122861, Cas# :
1192491-61-4
)
Avibactam is a non--lactam -lactamase inhibitor antibiotic, which is a new drug appli
Avatrombopag
(Catalog# : 16122860, Cas# :
570406-98-3
)
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-ac
Atorvastatin calcium trihydrate
(Catalog# : 16122859, Cas# :
344423-98-9
)
Atorvastatin is used primarily for lowering blood cholesterol and for prevention of e
Argatroban
(Catalog# : 16122858, Cas# :
141396-28-3
)
Argatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was ap
Amiselimod HCl
(Catalog# : 16122856, Cas# :
942398-84-7
)
Amiselimod, also known as MT1303, is a potent and selective immunosuppressant and sph
AM-2394
(Catalog# : 16122855, Cas# :
1442684-77-6
)
AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phos
Alvelestat (AZD9688)
(Catalog# : 16122854, Cas# :
848141-11-7
)
Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (
Alpha-Mangostin
(Catalog# : 16122802, Cas# :
6147-11-1
)
Alpha-Mangostin is a natural xanthonoid, a type of organic compound isolated from var
Aloxistatin (E-64d)
(Catalog# : 16122801, Cas# :
88321-09-9
)
Aloxistatin (E-64d), is a selective cysteine protease inhibitor or calpain and autoph
Alanosine
(Catalog# : 161227117, Cas# :
5854-93-3
)
Alanosine, also known as L-alanosine, is an amino acid analogue and antibiotic derive
Afuresertib HCl
(Catalog# : 161227116, Cas# :
1047645-82-8
)
Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the ser
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
----
SSTR
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
----
Hemoglobin
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MRX-2843
(Catalog# : 26A087, Cas# :
1429882-07-4
)
MRX-2843 is an orally bioavailable inhibitor of two receptor tyrosine kinases (RTKs),
GDC-0134
(Catalog# : 20432, Cas# :
1637394-01-4
)
GDC-0134 is a MAP3K12 (DLK) Inhibitor.
BI-847325
(Catalog# : 25046, Cas# :
2128698-24-6
)
BI-847325 is a novel, ATP-competitive, orally available inhibitor of Aurora kinases a
GDD-261
(Catalog# : 26A084, Cas# :
3137699-54-5
)
GDD-261 is an orally active, allosteric inhibitor of phosphoglycerate dehydrogenase (
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643 is a novel, orally available, non-covalent, macrocyclic, mutant selective OM
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
Aderamastat ( Synonyms: FP-025 )
(Catalog# : 26A086, Cas# :
877176-23-3
)
Aderamastat (FP-025) is an oral, selective, non-hydroxamate-based, non-competitive in
5-Formyl-4-methyl-1H-indole-2-carbonitrile
(Catalog# : 25095, Cas# :
1857296-22-0
)
MAT2A inhibitor-[Compound 1]
(Catalog# : 26A083, Cas# :
2923986-48-3
)
Compound 1 is a new MAT2A inhibitor.