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Inhibitors & Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
Ubiquitin
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Boronic Acids
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Name Index A
AZD-2461
(Catalog# : 16122863, Cas# :
1174043-16-3
)
AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. A
Avitinib maleate
(Catalog# : 16122862, Cas# :
1557268-88-8
)
Avitinib is an orally available, irreversible, epidermal growth factor receptor (EGFR
Avibactam sodium
(Catalog# : 16122861, Cas# :
1192491-61-4
)
Avibactam is a non--lactam -lactamase inhibitor antibiotic, which is a new drug appli
Avatrombopag
(Catalog# : 16122860, Cas# :
570406-98-3
)
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-ac
Atorvastatin calcium trihydrate
(Catalog# : 16122859, Cas# :
344423-98-9
)
Atorvastatin is used primarily for lowering blood cholesterol and for prevention of e
Argatroban
(Catalog# : 16122858, Cas# :
141396-28-3
)
Argatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was ap
Amiselimod HCl
(Catalog# : 16122856, Cas# :
942398-84-7
)
Amiselimod, also known as MT1303, is a potent and selective immunosuppressant and sph
AM-2394
(Catalog# : 16122855, Cas# :
1442684-77-6
)
AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phos
Alvelestat (AZD9688)
(Catalog# : 16122854, Cas# :
848141-11-7
)
Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (
Alpha-Mangostin
(Catalog# : 16122802, Cas# :
6147-11-1
)
Alpha-Mangostin is a natural xanthonoid, a type of organic compound isolated from var
Aloxistatin (E-64d)
(Catalog# : 16122801, Cas# :
88321-09-9
)
Aloxistatin (E-64d), is a selective cysteine protease inhibitor or calpain and autoph
Alanosine
(Catalog# : 161227117, Cas# :
5854-93-3
)
Alanosine, also known as L-alanosine, is an amino acid analogue and antibiotic derive
Afuresertib HCl
(Catalog# : 161227116, Cas# :
1047645-82-8
)
Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the ser
ACY-738
(Catalog# : 161227114, Cas# :
1375465-91-0
)
ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability
Acolbifene
(Catalog# : 161227113, Cas# :
182167-02-8
)
Acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modu
Abametapir
(Catalog# : 161227111, Cas# :
1762-34-1
)
Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metallopro
Alantolactone
(Catalog# : 161227107, Cas# :
546-43-0
)
Alantolactone, a naturally occurring eudesmane-type sesquiterpene lactone (SL), could
AS101
(Catalog# : 161227106, Cas# :
106566-58-9
)
AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1bet
ACP-196
(Catalog# : 16122783, Cas# :
1420477-60-6
)
Acalabrutinib is a selective second-generation Brutons tyrosine kinase (BTK) inhibito
APS-2-79
(Catalog# : 16122775, Cas# :
2002381-31-7
)
APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antago
Aprotinin
(Catalog# : 16122761, Cas# :
9087-70-1
)
Aprotinin is a small protein serine protease inhibitor, used to reduce perioperative
A-366
(Catalog# : 16122743, Cas# :
1527503-11-2
)
A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor wi
AZD0156
(Catalog# : 16122713, Cas# :
1821428-35-6
)
AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/rad
APTSTAT3-9R
(Catalog# : 16122704)
APTSTAT3-9R is a specific STAT3-binding peptide with addition of a cell-penetrating m
AGN 205728
(Catalog# : 6111520, Cas# :
859498-05-8
)
AGN 205728 is a potent and selective RAR antagonist with Ki/IC95 values of 3 nM/ 0.6
AGN 205327
(Catalog# : 6111519)
AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RAR// r
AGN 195183
(Catalog# : 6111517, Cas# :
367273-07-2
)
AGN 195183 is a potent and selective agonist of RAR(Kd=3 nM) with improved binding se
AGN 194310
(Catalog# : 6111516, Cas# :
229961-45-9
)
AGN 194310(VTP-194310) is a potent and selective pan-RARs agonist with Kd values of 3
Acetazolamide D3
(Catalog# : 6111513, Cas# :
1189904-01-5
)
Acetazolamide D3 is deuterium labeled Acetazolamide, which is a potent carbonic anhyd
APS-2-79
(Catalog# : 6111501, Cas# :
2002381-25-9
)
APS-2-79 is an antagonist of MEK phosphorylation by RAF through direct binding of the
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-
Atuzabrutinib
(Catalog# : 25145, Cas# :
1581714-49-9
)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
Andamertinib
(Catalog# : 25144, Cas# :
2254145-43-0
)
Andamertinib is an epidermal growth factor receptor tyrosine kinase inhibitor. It is
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)