STX-721
Catalog No: 20576
CAS Number: 2765525-82-2
Purity: ≧98.0%
STX-721 is a next-generation, orally delivered therapy, designed with potential best-in-class selectivity for exon 20 insertion mutations in epidermal growth factor receptors (“EGFR”), a well-known, clinically validated oncogenic driver in non-small cell lung cancer (“NSCLC”).
For research use only. We do not sell to patients.
Chemical Information
| Name | STX-721 |
|---|---|
| Iupac Chemical Name | 3-[(3-chloro-2-methoxyphenyl)amino]-2-(3-{2-[(2R)-1-[(2E)-4-(dimethylamino)but-2-enoyl]-2-methylpyrrolidin-2-yl]ethynyl}pyridin-4-yl)-1H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one |
| Synonyms | STX-721 ; STX721 ; STX 721 |
| Molecular Formula | C32H35ClN6O3 |
| Molecular Weight | 587.12 |
| Smile | O=C1C2=C(NC(C3=C(C#C[C@]4(C)N(C(/C=C/CN(C)C)=O)CCC4)C=NC=C3)=C2NC5=CC=CC(Cl)=C5OC)CCN1 |
| InChiKey | UMSJPISUMQOUKS-LMZGTLAXSA-N |
| InChi | InChI=1S/C32H35ClN6O3/c1-32(14-7-19-39(32)26(40)10-6-18-38(2)3)15-11-21-20-34-16-12-22(21)28-29(27-24(36-28)13-17-35-31(27)41)37-25-9-5-8-23(33)30(25)42-4/h5-6,8-10,12,16,20,36-37H,7,13-14,17-19H2,1-4H3,(H,35,41)/b10-6+/t32-/m1/s1 |
| CAS Number | 2765525-82-2 |
| Related CAS | 2765525-82-2 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Yellow solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
