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Membrane Transporter/Ion Channel
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
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Name Index A
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Name Index A
AMG 900
(Catalog# : 011803, Cas# :
945595-80-2
)
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/
APTO-253
(Catalog# : 011802, Cas# :
1422731-37-0
)
APTO-253 is a small molecule inhibitor of human metal-regulatory transcription factor
AC-55541
(Catalog# : 011302, Cas# :
916170-19-9
)
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist.
AZ 628
(Catalog# : 011120, Cas# :
878739-06-1
)
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM
AZD-5582
(Catalog# : 011117, Cas# :
1258392-53-8
)
AZD5582 is a potent IAP inhibitor, which is a dimeric compound based on the AVPI moti
Arbidol hydrochloride
(Catalog# : 011111, Cas# :
131707-23-8
)
Arbidol is an broad-spectrum antiviral chemical agent which can inhibit cell entry of
APY29
(Catalog# : 011108, Cas# :
1216665-49-4
)
APY29 is an allosteric modulator of IRE1; inhibits IRE1 autophosphorylation (IC50 = 2
AMG-47a
(Catalog# : 011107, Cas# :
882663-88-9
)
AMG-47a is a potent inhibitor of Lck and T cell proliferation.
ARQ-736
(Catalog# : 011104, Cas# :
1228237-57-7
)
ARQ 736 is a potent and selective BRAF inhibitor.
AZD4547
(Catalog# : 010820, Cas# :
1035270-39-3
)
AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2
AZD-1480
(Catalog# : 010816, Cas# :
935666-88-9
)
AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM, selectivity a
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )is a potent and selective dual RAF/ME
AZD8330
(Catalog# : 010809, Cas# :
869357-68-6
)
AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 n
AS703026
(Catalog# : 010808, Cas# :
1236699-92-5
)
AS703026 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2)
AZ505
(Catalog# : 010803, Cas# :
1035227-43-0
)
AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=
AG-L-59687
(Catalog# : 010428, Cas# :
793035-88-8
)
Coming soon!
AG1024
(Catalog# : 010422, Cas# :
65678-07-1
)
AG-1024 inhibits IGF-1R autophosphorylation with IC50 of 7 M, less potent to IR with
Almotriptan
(Catalog# : 010418, Cas# :
154323-57-6
)
Almotriptan is a 5-HT1B/1D-receptor agonist used to treat migraine.
AM630
(Catalog# : 010410, Cas# :
164178-33-0
)
AM630 is a selectivity CB2 antagonist with Ki of 31.2 nM; > 150 fold selectivity o
AZD-8055
(Catalog# : 123019, Cas# :
1009298-09-2
)
AZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential a
Amuvatinib
(Catalog# : 123016, Cas# :
850879-09-3
)
Amuvatinib is a potent and multi-targeted inhibitor of c-Kit, PDGFR and Flt3 with IC5
AR-42
(Catalog# : 123009, Cas# :
935881-37-1
)
AR-42 is a novel, oral cancer therapy currently in early clinical development.
A-966492
(Catalog# : 123006, Cas# :
934162-61-5
)
A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 n
AMG 487
(Catalog# : 122942, Cas# :
473719-41-4
)
AMG 487 is a small molecule antagonist of the chemokine receptor CXCR3.
Atosiban acetate
(Catalog# : 122931, Cas# :
90779-69-4
)
Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/
AST-1306
(Catalog# : 122926, Cas# :
897383-62-9
)
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and
AZD8186
(Catalog# : 122925, Cas# :
1627494-13-6
)
AZD8186 is an isoform-specific small-molecule PI3K inhibitor, potently inhibits PI3K
AG-120
(Catalog# : 122906, Cas# :
1448346-63-1
)
AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), wi
AZD-5423
(Catalog# : 122902, Cas# :
1034148-04-3
)
Coming soon!
A 83-01
(Catalog# : 122843, Cas# :
909910-43-6
)
A 83-01 is a selective inhibitor of TGF- type I receptor ALK5 kinase, type I activin/
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran
JX06
(Catalog# : 25199, Cas# :
729-46-4
)
JX06 is an effective, selective, covalent PDK inhibitor.
Bezuclastinib
(Catalog# : 25198, Cas# :
1616385-51-3
)
Bezuclastinib is an oral, small-molecule inhibitor of the kinase activity of the KIT
Bexobrutideg ( NX-5948 )
(Catalog# : 25197, Cas# :
2649400-34-8
)
Bexobrutideg (NX-5948) is a BTK degrader.
Rosolutamide ( AJ-201 ; ASC-JM17 )
(Catalog# : 25196, Cas# :
1039760-91-2 , 2074613-88-8 [ALTERNATIVE]
)
Rosolutamide (formerly known as AJ-201, ASC-JM-17 or ALZ-002) is a nuclear factor ery
Soclenicant (BNC-210 ; IW-2143)
(Catalog# : 25195, Cas# :
1020634-41-6
)
Soclenicant (BNC-210 ; IW-2143) is a novel α7 nicotinic acetylcholine receptor-negat
Umbralisib
(Catalog# : 25085, Cas# :
1532533-67-7
)
Umbralisib, also known as TGR1202 and RP5264 , is a highly specific, orally available