Avoralstat
Catalog No: 011813
CAS Number: 918407-35-9
Purity: 95.0%
Avoralstat (formerly BCX4161) is a potent small-molecule oral plasma kallikrein inhibitor under development for treatment of hereditary angioedema (HAE).
Avoralstat (formerly BCX4161)，contact us by email for the Bulk quotation.
For research use only. We do not sell to patients.
Chemical Information
| Name | Avoralstat |
|---|---|
| Iupac Chemical Name | 3-{2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl}-6-[(cyclopropylmethyl)carbamoyl]pyridine-2-carboxylic acid |
| Synonyms | BCX-4161; BCX 4161; BCX4161 |
| Molecular Formula | C28H27N5O5 |
| Molecular Weight | 513.554 |
| Smile | O=C(C1=NC(C(NCC2CC2)=O)=CC=C1C3=CC(OC)=C(C=C)C=C3C(NC4=CC=C(C(N)=N)C=C4)=O)O |
| InChiKey | TUWMKPVJGGWGNL-UHFFFAOYSA-N |
| InChi | InChI=1S/C28H27N5O5/c1-3-16-12-21(26(34)32-18-8-6-17(7-9-18)25(29)30)20(13-23(16)38-2)19-10-11-22(33-24(19)28(36)37)27(35)31-14-15-4-5-15/h3,6-13,15H,1,4-5,14H2,2H3,(H3,29,30)(H,31,35)(H,32,34)(H,36,37) |
| CAS Number | 918407-35-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | light-yellow solid to off-white solid |
|---|---|
| Purity | 95.0% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | plasma kallikrein inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
