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Angiogenesis
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Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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Deuterated
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Amino Acids
Anilines
Boronic Acids
Bromides
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Deuterated
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Name Index A
AZD-0284
(Catalog# : 19365, Cas# :
2101291-07-8
)
AZD-0284 is a potent, selective, inverse agonist of the nuclear receptor RORγ for th
AZ304
(Catalog# : 19363, Cas# :
942507-42-8
)
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type B
AZ876
(Catalog# : 19356, Cas# :
898800-26-5
)
AZ876, also known as AZ-876, is a liver X receptor agonist. AZ876 protects against pa
AGN-190299
(Catalog# : 19316, Cas# :
118292-41-4
)
Tazarotene is a retinoid prodrug which is converted to its active form, the cognate c
AM281
(Catalog# : 19315, Cas# :
202463-68-1
)
AM281 is a synthetic cannabinoid CB1 receptor antagonist.
ASP9521
(Catalog# : 19312, Cas# :
1126084-37-4
)
ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid d
AZD0364
(Catalog# : 192275, Cas# :
2097416-76-5
)
AZD0364 is an ERK1 and/or ERK2 kinase for the treatment of cancer. ERK1 and ERK2 kina
ATF6-activator-147
(Catalog# : 192212, Cas# :
393121-74-9
)
ATF6-activator-147 is an ATF6 simulator which acts as a prodrug that preferentially t
AZD1152
(Catalog# : 192156, Cas# :
722543-31-9
)
AZD1152 is a pro-drug of Barasertib-hQPA, which is a highly selective Aurora B inhibi
AZD3229
(Catalog# : 191287, Cas# :
2248003-60-1
)
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal st
AM095 sodium
(Catalog# : 191251, Cas# :
1345614-59-6
)
AM095 is a potent LPA1 receptor antagonist because it inhibited GTPγS binding to Chi
AZD4573 free base
(Catalog# : 191212, Cas# :
2057509-72-3
)
AZD-4573 is a selective, short-acting inhibitor of the serine/threonine cyclin-depend
AR-9281
(Catalog# : 191146, Cas# :
913548-29-5
)
AR-9281 is a soluble epoxide hydrolase (s-EH) inhibitor potentially for the treatment
ARRY-797 (ARRY-371797)
(Catalog# : 191112, Cas# :
1036404-17-7
)
ARRY-797 is an oral, selective p38 mitogen-activated protein kinase inhibitor. ARRY-7
Abivertinib
(Catalog# : 19141, Cas# :
1557267-42-1
)
Abivertinib, also known as AC0010 and Avitinib, is a tyrosine kinase inhibitor, antin
AZD7507
(Catalog# : 1812294, Cas# :
1041852-85-0
)
AZD7507 is a potent and selective CSF-1R inhibitor (32 nM cell activity), AZD7507 is
Auranofin
(Catalog# : 1812281, Cas# :
34031-32-8
)
Auranofin, also known as Ridaura and SKF-39162, is an oral chrysotherapeutic agent fo
AX-024 HCl
(Catalog# : 181254, Cas# :
1704801-24-0
)
AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively i
AG 879
(Catalog# : 1811303, Cas# :
148741-30-4
)
AG-879 is a tyrphostin compound that inhibits nerve growth factor-dependent TrkA tyro
Avagacestat
(Catalog# : 1811283, Cas# :
1146699-66-2
)
Avagacestat, also known as BMS-708163, is an oral GSI designed for selective inhibiti
AS1842856
(Catalog# : 1811265, Cas# :
836620-48-5
)
AS1842856 is a cell-permeable Foxo1inhibitor that blocks the transcription activity o
Anlotinib HCl ( AL-3818 )
(Catalog# : 1811211, Cas# :
1360460-82-7
)
Anlotinib is a novel oral tyrosine kinase inhibitor (TKI) targeting c-kit, platelet-d
Avatrombopag maleate
(Catalog# : 5141902, Cas# :
677007-74-8
)
Avatrombopag maleate is an orally bioavailable, small molecule thrombopoietin recepto
AZD-3514
(Catalog# : 1810251, Cas# :
1240299-33-5
)
AZD-3514 is a potent androgen receptor downregulator with potential anticancer cancer
AZ32
(Catalog# : 1810223, Cas# :
no
)
AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with
ARS-1620
(Catalog# : 1810222, Cas# :
1698055-85-4
)
ARS-1620 is an atropisomeric selective KRAS-G12C inhibitor with desirable pharmacokin
AGL-2263
(Catalog# : 1810175, Cas# :
638213-98-6
)
AGL-2263 is a novel insulin receptor inhibitor.
AM211
(Catalog# : 1810173, Cas# :
1175526-27-8
)
AM-211 is a novel and potent antagonist of the prostaglandin D2 receptor type 2.
Arimoclomol maleate
(Catalog# : 188281, Cas# :
289893-26-1
)
Arimoclomol, also known as BRX-220, is potentially useful for the treatment of Nieman
ASP7663
(Catalog# : 187123, Cas# :
1190217-35-6
)
ASP7663 is an orally bioavailable selective TRPA1 activator.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zedoresertib
(Catalog# : 26A023, Cas# :
2243882-74-6
)
Zedoresertib (Debio 0123) is a brain-penetrant, highly selective WEE1 kinase inhibito
BEN-28010
(Catalog# : 26A022, Cas# :
3033961-38-2
)
BEN-28010 is a freely brain-penetrant, potent, and selective CHK1 inhibitor.
Tert-butyl 4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate
(Catalog# : 26B007, Cas# :
3107291-07-3
)
Muvalaplin
(Catalog# : 20528, Cas# :
2565656-70-2
)
Muvalaplin is a small molecule that inhibits formation of Lp(a) by interfering with t
MAT2A-IN-22
(Catalog# : 26A021, Cas# :
2925330-18-1
)
MAT2A-IN-22 (Compound 29-1) is a blood-brain barrier-penetrant and orally active MAT2
AD-8007
(Catalog# : 26A018, Cas# :
1497439-74-3
)
AD-8007 is a selective and brain-penetrant inhibitor of acetyl CoA synthase 2 (ACSS2).
ZY-444
(Catalog# : 26A020, Cas# :
1802650-31-2
)
ZY-444 is an anti-cancer agent by inhibiting PC ( pyruvate carboxylase ) activity.
AD-5584
(Catalog# : 26A019, Cas# :
2306525-79-9
)
AD-5584 is a novel brain-permeable ACSS2 inhibitors.
IDB-003
(Catalog# : 26A017, Cas# :
3079716-11-0
)
IDB-003 inhibits MDA-MB-231 tumor growth in vivo.
Vafidemstat
(Catalog# : 18891, Cas# :
1357362-02-7
)
Vafidemstat, also known as ORY 2001, is a lysine-specific histone demethylase (LSD1)