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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
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Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Name Index A
AZD5718
(Catalog# : 20476, Cas# :
2041075-86-7
)
AZD5718 is a novel Inhibitor of 5-Lipoxygenase Activating Protein(FLAP) for Treatment
ALZ-801
(Catalog# : 20450, Cas# :
1034190-08-3
)
ALZ-801 is an oral, small-molecule inhibitor of beta amyloid (Aβ) oligomer formation
AZD-2207
(Catalog# : 20440, Cas# :
866598-45-0
)
AZD-2207 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for
AZD6703
(Catalog# : 20439, Cas# :
851845-37-9
)
AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mi
Afizagabar
(Catalog# : 20429, Cas# :
1398496-82-6
)
Afizagabar, also known as S44819 and Egis 13529, is a GABA receptor antagonist.
AMD 070
(Catalog# : 20427, Cas# :
558447-26-0
)
1-(6-aminopyridin-2-yl)ethanone
(Catalog# : 171453, Cas# :
1060801-23-1
)
1-(6-aminopyridin-2-yl)ethanone, CAS 1060801-23-1.
Anle138b
(Catalog# : 171553, Cas# :
882697-00-9
)
Anle138b is an oral, brain-penetrant, general inhibitor of protein aggregation. It wa
5-AMino-3-broMo-2-Morpholinopyridine
(Catalog# : 20425, Cas# :
1215932-56-1
)
2-Amino-5-bromo-4-methoxy-3-pyridinecarbonitrile
(Catalog# : 20424, Cas# :
951884-75-6
)
4-AMINO-6-IODOPYRIMIDINE
(Catalog# : 20421, Cas# :
53557-69-0
)
Acetic acid, 2-[[2-(1,1-diMethylethyl)phenyl]aMino]-2-oxo-
(Catalog# : 20415, Cas# :
254751-08-1
)
ACETOPHENONESEMICARBAZONE
(Catalog# : 20413, Cas# :
2492-30-0
)
2-amino-4-(4-fluorophenyl)thiazole-5-carbonitrile
(Catalog# : 20400, Cas# :
952753-59-2
)
4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine
(Catalog# : 20397, Cas# :
1770840-43-1
)
2-Amino-6-fluoro-3-nitropyridine
(Catalog# : 20389, Cas# :
60186-21-2
)
4-Aza-1-azoniabicyclo[2.2.2]octane, 1,1'-(1,12-dodecanediyl)bis-, dibromide (9CI)
(Catalog# : G20382, Cas# :
256448-15-4
)
Asciminib HCl
(Catalog# : 1711223, Cas# :
2119669-71-3
)
Asciminib, also known as ABL001, is a potent allosteric inhibitor of BCR-ABL.
AGN 196996
(Catalog# : 226191, Cas# :
958295-17-5
)
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little b
Ablukast
(Catalog# : 20319, Cas# :
96566-25-5 (free acid)
)
Ablukast is a leuktriene receptor antagonist that acts as an anti-asthmatic.
2-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID
(Catalog# : 20312, Cas# :
83265-53-6
)
Afabicin
(Catalog# : 20303, Cas# :
1518800-35-5
)
Afabicin (formerly Debio 1450, AFN-1720) is a prodrug of afabicin desphosphono, an en
Acoramidis (AG-10 )
(Catalog# : 20300, Cas# :
1446711-81-4
)
Acoramidis (formerly AG10) is an investigational, orally-administered small molecule
ASTX-029
(Catalog# : 20298, Cas# :
2095719-92-7
)
ASTX029 is a highly potent and selective dual-mechanism ERK inhibitor. ASTX029 inhibi
AZD-4818
(Catalog# : 20297, Cas# :
1003566-93-5
)
AZD-4818 is a chemokine CCR1 antagonist that is used for the treatment of chronic obs
Adavivint
(Catalog# : 20289, Cas# :
1467093-03-3 (free base)
)
A2793
(Catalog# : 20286, Cas# :
88349-90-0
)
A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TW
ABT-384
(Catalog# : 20281, Cas# :
868623-40-9
)
ABT-384 is a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase type
AN 0128
(Catalog# : 20269, Cas# :
872044-70-7
)
AN 0128, also known as CRM-0005 and ONT-0001, is a tumour necrosis factor alpha (TNF-
Almonertinib
(Catalog# : 20267, Cas# :
1899921-05-1
)
Almonertinib is an orally available inhibitor of the epidermal growth factor receptor
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran