ACY-775
Catalog No: 77821
CAS Number: 1375466-18-4
Purity: 98.0% by HPLC
ACY-775 is a potent and selective HDAC6 inhbiitor. ACY-775 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs. ACY-775 shares the antidepressant-like properties of other HDAC inhibitors, such as SAHA and MS-275, in the tail suspension test and social defeat paradigm
For research use only. We do not sell to patients.
Chemical Information
| Name | ACY-775 |
|---|---|
| Iupac Chemical Name | 2-((1-(3-Fluorophenyl)cyclohexyl)amino)-n-hydroxypyrimidine-5-carboxamide |
| Synonyms | ACY-775;ACY775;ACY 775 |
| Molecular Formula | C17H19FN4O2 |
| Molecular Weight | 330.36 |
| Smile | FC=1C=C(C=CC1)C1(CCCCC1)NC1=NC=C(C=N1)C(=O)NO |
| InChiKey | IYBURCQQEUNLDL-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H19FN4O2/c18-14-6-4-5-13(9-14)17(7-2-1-3-8-17)21-16-19-10-12(11-20-16)15(23)22-24/h4-6,9-11,24H,1-3,7-8H2,(H,22,23)(H,19,20,21) |
| CAS Number | 1375466-18-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | A crystalline solid |
|---|---|
| Purity | 98.0% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
