Afuresertib HCl
Catalog No: 161227116
CAS Number: 1047645-82-8
Purity: ≧98.0%
Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | Afuresertib HCl |
|---|---|
| Iupac Chemical Name | (S)-N-(1-Amino-3-(3-fluorophenyl)propan-2-YL)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-YL)thiophene-2-carboxamide hydrochloride |
| Synonyms | GSK2110183; GSK 2110183; GSK-2110183; GSK2110183B; GSK 2110183B; GSK2110183B; Afuresertib |
| Molecular Formula | C18H18Cl3FN4OS |
| Molecular Weight | 463.78 |
| Smile | Cl.NC[C@H](CC1=CC(=CC=C1)F)NC(=O)C=1SC(=C(C1)C1=C(C=NN1C)Cl)Cl |
| InChiKey | YFQJOPFTGMHYNV-YDALLXLXSA-N |
| InChi | InChI=1S/C18H17Cl2FN4OS.ClH/c1-25-16(14(19)9-23-25)13-7-15(27-17(13)20)18(26)24-12(8-22)6-10-3-2-4-11(21)5-10;/h2-5,7,9,12H,6,8,22H2,1H3,(H,24,26);1H/t12-;/m0./s1 |
| CAS Number | 1047645-82-8 |
| Related CAS | 1047645-82-8 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Crystalline solid |
|---|---|
| Purity | ≧98.0% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
