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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Name Index A
Apaziquone
(Catalog# : 16071104, Cas# :
114560-48-4
)
Apaziquone, also known as EO9, EOquin, is a n indolequinone bioreductive prodrug and
AF-353
(Catalog# : 16071021, Cas# :
865305-30-2
)
AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, in
AMG-517
(Catalog# : 16071001, Cas# :
659730-32-2
)
AMG 517 is a potent and selective TRPV1 antagonist, and antagonizes capsaicin, proton
ascorbic acid
(Catalog# : 16070919, Cas# :
89924-69-6
)
(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
ARS-853
(Catalog# : 16070910, Cas# :
1629268-00-3
)
ARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS dri
Asunaprevir
(Catalog# : 16070810, Cas# :
630420-16-5
)
Asunaprevir, also known as BMS-650032, is an inhibitor of the hepatitis C virus enzym
AZD2281(Olaparib)
(Catalog# : 92801, Cas# :
763113-22-0
)
Olaparib (AZD-2281, trade name Lynparza) is an FDA-approved targeted therapy for canc
AZ91498
(Catalog# : 16070801, Cas# :
773871-93-5
)
AZ91498
A-769662
(Catalog# : 16070701, Cas# :
844499-71-4
)
A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with a
AM-580
(Catalog# : 16062701, Cas# :
102121-60-8
)
AM-580 is a potent RARalpha agonist. AM580 has powerful and selective cyto-differenti
Aurora A Inhibitor I
(Catalog# : 16062401, Cas# :
1158838-45-9
)
Aurora A Inhibitor I
AN-2718
(Catalog# : 16062104, Cas# :
174672-06-1
)
AN-2718
AZ7371
(Catalog# : 16062102, Cas# :
1494675-86-3
)
AZ7371 is a a novel non-covalent DprE1 inhibitor
Amcinafide
(Catalog# : 16062001, Cas# :
7332-27-6
)
Amcinafide
AZD-3965
(Catalog# : 33001, Cas# :
1448671-31-5
)
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a bindi
AVN944
(Catalog# : 022201, Cas# :
297730-17-7
)
AVN944 is an orally available, synthetic small molecule with potential antineoplastic
Arry-380
(Catalog# : 021801, Cas# :
937265-83-3
)
ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent again
A-1331852
(Catalog# : 012603, Cas# :
1430844-80-6
)
Coming soon!
A-1155463
(Catalog# : 012602, Cas# :
1235034-55-5
)
A-1155463 is a highly potent and selective BCL-XL inhibitor.
AH13205
(Catalog# : 011919, Cas# :
148436-63-9
)
Coming soon!
Alofanib
(Catalog# : 011918, Cas# :
1612888-66-0
)
Alofanib is a potential small molecule kinase inhibitor with potential anticancer act
AS 602801
(Catalog# : 011913, Cas# :
848344-36-5
)
AS 602801 is a novel, orally active inhibitor of JNK.
AMG232
(Catalog# : 011911, Cas# :
1352066-68-2
)
AMG232 is an extremely potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC50 = 9.
Afdx 384
(Catalog# : 011905, Cas# :
118290-27-0
)
Coming soon!
Avoralstat
(Catalog# : 011813, Cas# :
918407-35-9
)
Avoralstat(前身为BCX4161)是一种有效的小分子口服血浆激肽释放酶
AMG-337
(Catalog# : 01181, Cas# :
1173699-31-4
)
AMG-337 is a potent and highly selective small molecule ATP-competitive MET kinase in
Afuresertib
(Catalog# : 011811, Cas# :
1047644-62-1
)
Afuresertib is a potent pan-AKT inhibitor that demonstrated synergy with bortezomib i
AMG 900
(Catalog# : 011803, Cas# :
945595-80-2
)
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/
APTO-253
(Catalog# : 011802, Cas# :
1422731-37-0
)
APTO-253 is a small molecule inhibitor of human metal-regulatory transcription factor
AC-55541
(Catalog# : 011302, Cas# :
916170-19-9
)
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
EP6
(Catalog# : 25161, Cas# :
1353567-32-4
)
EP6 is a 5-lipoxygenase (5-LO) inhibitor. 5-LO is a crucial enzyme of the arachidonic
Elzovantinib
(Catalog# : 25160, Cas# :
2271119-26-5
)
Elzovantinib, also known as TPX-0022 and CSF1R-IN-2, is an orally bioavailable CSF1R
APS6-45
(Catalog# : 25159, Cas# :
2188236-41-9
)
APS6-45 is a tumor calibrated inhibitor, showing unique polypharmacology. APS6-45 sho
ARN14494
(Catalog# : 25156, Cas# :
1037837-27-6
)
ARN14494 是一种选择性丝氨酸棕榈酰转移酶 (SPT) 抑制剂,它是鞘脂
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) 特异性抑制 PTDSS1,而 PTDSS1 可催化丝氨酸掺入 PC。
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,
Avutometinib ( 别名: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib(别名:RO-5126766、CH-5126766)是一种正在开发的 Ras-Raf-ME
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 是具有血脑屏障渗透性的 MAPK 通路分子胶,能够抑制 RAF 磷
Nivegacetor ( 别名: RG-6289, RO-7269162)
(Catalog# : 25151, Cas# :
2443487-67-8
)
Nivegacetor(RG-6289,RO-7269162)是一种口服γ分泌酶调节剂。
GSK4362676 ( MAT2A-IN-9 )
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 ( GSK4362676 )是一种2-氧代喹唑啉衍生物,是一种强效的MAT2