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Autophagy
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DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
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Boronic Acids
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Name Index A
ARQ-092
(Catalog# : 611805, Cas# :
1313881-70-7
)
ARQ-092 is an Akt inhibitor extracted from patent US/20150299195A1, compound A.
Akt1 and Akt2-IN-1
(Catalog# : 611804, Cas# :
893422-47-4
)
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50 = 3.5 nM) and Akt2 (IC50
AKT inhibitor
(Catalog# : 611803, Cas# :
1004990-28-6
)
AKT inhibitor is a broadly selective, potent, ATP-competitive Akt inhibitor, displays
A-674563 hydrochloride
(Catalog# : 611802, Cas# :
2070009-66-2
)
A-674563 hydrochloride is a potent selective Akt1 inhibitor with an IC50 of 14 nM; al
Avasimibe
(Catalog# : 161014003, Cas# :
166518-60-1
)
Avasimibe is a selective inhibitor of Cholesterol Acyltransferase 1 and CYP2C9. Avasi
Apoptozole
(Catalog# : 161014002, Cas# :
1054543-47-3
)
Apoptosis Activator VII, Apoptozole is a cell-permeable imidazole compound that direc
AT7867
(Catalog# : 161009021, Cas# :
857531-00-1 (free base); 1431697-86-7 (2HCl)
)
This ATP-competitive small molecule potently inhibits both AKT and p70S6K activity at
AKT inhibitor VIII
(Catalog# : 161009020, Cas# :
612847-09-3
)
AKT inhibitor VIII suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric c
AS-604850
(Catalog# : 160926014, Cas# :
648449-76-7
)
Treatment with this PI3K inhibitor enhanced myelination and axon number in the spinal
AS-252424
(Catalog# : 160926012, Cas# :
900515-16-4
)
AS-252424 is a potent and selective small-molecule PI3Kgamma inhibitor. Oral administ
AS-605240
(Catalog# : 160926007, Cas# :
648450-29-7
)
Orally administration of AS605240 significantly prevented lung inflammation and reduc
Acalisib
(Catalog# : 16071413, Cas# :
870281-34-8
)
Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of th
AZD8330
(Catalog# : 16071301, Cas# :
1204531-17-8
)
AZD8330
AZD-4547
(Catalog# : 16071109, Cas# :
1394854-62-6
)
AZD-4547
Apaziquone
(Catalog# : 16071104, Cas# :
114560-48-4
)
Apaziquone, also known as EO9, EOquin, is a n indolequinone bioreductive prodrug and
AF-353
(Catalog# : 16071021, Cas# :
865305-30-2
)
AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, in
AMG-517
(Catalog# : 16071001, Cas# :
659730-32-2
)
AMG 517 is a potent and selective TRPV1 antagonist, and antagonizes capsaicin, proton
ascorbic acid
(Catalog# : 16070919, Cas# :
89924-69-6
)
(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
ARS-853
(Catalog# : 16070910, Cas# :
1629268-00-3
)
ARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS dri
Asunaprevir
(Catalog# : 16070810, Cas# :
630420-16-5
)
Asunaprevir, also known as BMS-650032, is an inhibitor of the hepatitis C virus enzym
AZD2281(Olaparib)
(Catalog# : 92801, Cas# :
763113-22-0
)
Olaparib (AZD-2281, trade name Lynparza) is an FDA-approved targeted therapy for canc
AZ91498
(Catalog# : 16070801, Cas# :
773871-93-5
)
AZ91498
A-769662
(Catalog# : 16070701, Cas# :
844499-71-4
)
A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with a
AM-580
(Catalog# : 16062701, Cas# :
102121-60-8
)
AM-580 is a potent RARalpha agonist. AM580 has powerful and selective cyto-differenti
Aurora A Inhibitor I
(Catalog# : 16062401, Cas# :
1158838-45-9
)
Aurora A Inhibitor I
AN-2718
(Catalog# : 16062104, Cas# :
174672-06-1
)
AN-2718
AZ7371
(Catalog# : 16062102, Cas# :
1494675-86-3
)
AZ7371 is a a novel non-covalent DprE1 inhibitor
Amcinafide
(Catalog# : 16062001, Cas# :
7332-27-6
)
Amcinafide
AZD-3965
(Catalog# : 33001, Cas# :
1448671-31-5
)
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a bindi
AVN944
(Catalog# : 022201, Cas# :
297730-17-7
)
AVN944 is an orally available, synthetic small molecule with potential antineoplastic
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
----
SSTR
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
----
Hemoglobin
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MRX-2843
(Catalog# : 26A087, Cas# :
1429882-07-4
)
MRX-2843 is an orally bioavailable inhibitor of two receptor tyrosine kinases (RTKs),
GDC-0134
(Catalog# : 20432, Cas# :
1637394-01-4
)
GDC-0134 is a MAP3K12 (DLK) Inhibitor.
BI-847325
(Catalog# : 25046, Cas# :
2128698-24-6
)
BI-847325 is a novel, ATP-competitive, orally available inhibitor of Aurora kinases a
GDD-261
(Catalog# : 26A084, Cas# :
3137699-54-5
)
GDD-261 is an orally active, allosteric inhibitor of phosphoglycerate dehydrogenase (
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643 is a novel, orally available, non-covalent, macrocyclic, mutant selective OM
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
Aderamastat ( Synonyms: FP-025 )
(Catalog# : 26A086, Cas# :
877176-23-3
)
Aderamastat (FP-025) is an oral, selective, non-hydroxamate-based, non-competitive in
5-Formyl-4-methyl-1H-indole-2-carbonitrile
(Catalog# : 25095, Cas# :
1857296-22-0
)
MAT2A inhibitor-[Compound 1]
(Catalog# : 26A083, Cas# :
2923986-48-3
)
Compound 1 is a new MAT2A inhibitor.