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Angiogenesis
Anti-infection
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Autophagy
Cell Cycle
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Epigenetics
GPCR & G Protein
Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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TGF-beta/Smad
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index A
Asciminib ( ABL001 )
(Catalog# : 1711222, Cas# :
1492952-76-7
)
Asciminib, Bulk in stock, contact us by email for the quotation. Kg scale intermediat
Autophinib
(Catalog# : 17101617, Cas# :
1644443-47-9
)
Autophinib is a novel potent autophagy inhibitor, inhibiting autophagy induced by sta
Adarigiline
(Catalog# : 1710167, Cas# :
1124197-79-0
)
Adarigiline is a monoamine oxidase B inhibitor drug candidate.
Adafosbuvir
(Catalog# : 1710166, Cas# :
1613589-09-5
)
Adafosbuvir is an antiviral drug candidate.
AZD-5153 HNT salt
(Catalog# : 1710161, Cas# :
1869912-40-2
)
AZD-5153 HNT salt, is a 6-hydroxy-2-naphthoic acid salt of AZD-5153.AZD5153 is highly
ABT-100
(Catalog# : 1710131, Cas# :
450839-40-4
)
ABT-100 is an orally bioavailable farnesyltransferase inhibitor.
Acebilustat
(Catalog# : 179159, Cas# :
943764-99-6
)
Acebilustat, also known as ZK322, is a potent and selective leukotriene A4 hydrolase
AR-7
(Catalog# : 179158, Cas# :
80306-38-3
)
AR-7, also known as Atypical retinoid 7 , is a potent and selective enhancer of the c
Adelmidrol
(Catalog# : 179151, Cas# :
1675-66-7
)
Adelmidrol is the semisynthetic diethanolamide derivative of azelaic acid, and has a
AZD7545
(Catalog# : 179136, Cas# :
252017-04-2
)
AZD7545 is an inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2) (IC50 value of 6.4
AMG-9810
(Catalog# : 179117, Cas# :
545395-94-6
)
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid recepto
AS-2444697 HCl
(Catalog# : 179832, Cas# :
1287665-60-4
)
AS-2444697 is a RAK-4 inhibitor. Six weeks' repeated administration of AS2444697 (0.3
Acecainide HCl
(Catalog# : 179829, Cas# :
34118-92-8
)
Acecainide, also known as N-acetylprocainamide and ASL 601, is the N-acetylated metab
ASC-J9
(Catalog# : 179816, Cas# :
52328-98-0
)
<span style="color:#34495E;font-family:"font-size:14px;background-color:
AMG-009
(Catalog# : 17987, Cas# :
1027847-67-1
)
AMG 009 is an orally active, small molecule CRTH2 (chemoattractant receptor-homologou
5-amino-2-fluoro-4-methylbenzonitrile
(Catalog# : 1781603, Cas# :
1426136-04-0
)
5-amino-2-fluoro-4-methylbenzonitrile
2-azaspiro[3.5]nonan-7-ol hydrochloride
(Catalog# : 1781602, Cas# :
1434141-67-9
)
2-azaspiro[3.5]nonan-7-ol hydrochloride
AZD3264
(Catalog# : 178910, Cas# :
1609281-86-8
)
AZD3264 is a novel and small molecule IKK2 inhibitor.IKK2 serves as a protein subunit
A-971432
(Catalog# : 178816, Cas# :
1240308-45-5
)
A‑971432 is highly selective for S1P5 and has excellent plasma and CNS exposure aft
A-1165442
(Catalog# : 20178812, Cas# :
1221443-94-2
)
A-1165442 is a temperature-neutral transient receptor potential vanilloid-1 (TRPV1) a
AZD4205
(Catalog# : 20178710, Cas# :
2091134-35-7
)
AZD4205 is a highly potent JAK1-selective kinase inhibitor with excellent preclinical
ACY-775
(Catalog# : 77821, Cas# :
1375466-18-4
)
ACY-775 is a potent and selective HDAC6 inhbiitor. ACY-775 inhibits HDAC6 with low na
AAI-101
(Catalog# : 1773101, Cas# :
1001404-83-6
)
AAI101(AAI-101) is a novel extended-spectrum -lactamase inhibitor.The combination of
AV-412 Tosylate
(Catalog# : 17030105, Cas# :
451493-31-5
)
AV-412, also known as MP-412, is a second-generation, orally bioavailable dual kinase
AZD-7594
(Catalog# : 17022812, Cas# :
1196509-60-0
)
AZD-7594, also known as AZ13189620, is an inhaled selective glucocorticoid receptor (
AZD3839
(Catalog# : 17022710, Cas# :
1227163-56-5
)
AZD3839 is a potent and selective BACE1 inhibitor. AZD3839 is clinical candidate for
A-1210477
(Catalog# : 17022404, Cas# :
1668553-26-1
)
A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 induces the hallmarks
Apatinib
(Catalog# : 17022301, Cas# :
811803-05-1
)
Apatinib is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM.
Amikacin sulfate
(Catalog# : 17021407, Cas# :
39831-55-5
)
Amikacin sulfate(BAY416651 sulfate) is a semi-synthetic aminoglycoside antibiotic der
AFN-1252
(Catalog# : 17021406, Cas# :
620175-39-5
)
AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (F
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran