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AZD-7594

Catalog No.: 17022812
Cas No.: 1196509-60-0
Purity : 98% 
17022812 - AZD-7594 | CAS 1196509-60-0

Catalog number : 17022812

CAS number : 1196509-60-0

Molecular Formula : C32H32F2N4O6 

Molecular Weight : 606.6268 

Iupac Chemical Name : 3-(5-((1R,2S)-2-(2,2-difluoropropanamido)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propoxy)-1H-indazol-1-yl)-N-(tetrahydrofuran-3-yl)benzamide 

Smile : FC(C(=O)N[C@H]([C@H](OC=1C=C2C=NN(C2=CC1)C=1C=C(C(=O)NC2COCC2)C=CC1)C1=CC2=C(OCCO2)C=C1)C)(C)F

InChiKey : ZZWJKLGCDHYVMB-QMQODZDESA-N

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SynonymsAZD-7594; AZD 7594; AZD7594; AZ13189620; AZ-13189620; AZ 13189620 
Molecular FormulaC32H32F2N4O6 
Molecular Weight606.6268 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileFC(C(=O)N[C@H]([C@H](OC=1C=C2C=NN(C2=CC1)C=1C=C(C(=O)NC2COCC2)C=CC1)C1=CC2=C(OCCO2)C=C1)C)(C)F
InChiKeyZZWJKLGCDHYVMB-QMQODZDESA-N
InChiInChI=1S/C32H32F2N4O6/c1-19(36-31(40)32(2,33)34)29(20-6-9-27-28(16-20)43-13-12-42-27)44-25-7-8-26-22(15-25)17-35-38(26)24-5-3-4-21(14-24)30(39)37-23-10-11-41-18-23/h3-9,14-17,19,23,29H,10-13,18H2,1-2H3,(H,36,40)(H,37,39)/t19-,23?,29-/m0/s1
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AZD-7594, also known as AZ13189620, is an inhaled selective glucocorticoid receptor (GCCR) modulator. AZD-7594 is in phase II clinical trials by AstraZeneca for the treatment of mild to moderate asthma. It is also in phase I clinical trials for the treatment of chronic obstructive pulmonary disorder (COPD). 

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