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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyridines
Pyrimidines
Quinolines
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
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Name Index A
AMG-9810
(Catalog# : 179117, Cas# :
545395-94-6
)
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid recepto
AS-2444697 HCl
(Catalog# : 179832, Cas# :
1287665-60-4
)
AS-2444697 is a RAK-4 inhibitor. Six weeks' repeated administration of AS2444697 (0.3
Acecainide HCl
(Catalog# : 179829, Cas# :
34118-92-8
)
Acecainide, also known as N-acetylprocainamide and ASL 601, is the N-acetylated metab
ASC-J9
(Catalog# : 179816, Cas# :
52328-98-0
)
<span style="color:#34495E;font-family:"font-size:14px;background-color:
AMG-009
(Catalog# : 17987, Cas# :
1027847-67-1
)
AMG 009 is an orally active, small molecule CRTH2 (chemoattractant receptor-homologou
5-amino-2-fluoro-4-methylbenzonitrile
(Catalog# : 1781603, Cas# :
1426136-04-0
)
5-amino-2-fluoro-4-methylbenzonitrile
2-azaspiro[3.5]nonan-7-ol hydrochloride
(Catalog# : 1781602, Cas# :
1434141-67-9
)
2-azaspiro[3.5]nonan-7-ol hydrochloride
Abemaciclib ( LY2835219)
(Catalog# : 178141, Cas# :
1231929-97-7
)
Abemaciclib, also known as LY2835219, is orally available cyclin-dependent kinase (CD
AZD3264
(Catalog# : 178910, Cas# :
1609281-86-8
)
AZD3264 is a novel and small molecule IKK2 inhibitor.IKK2 serves as a protein subunit
A-971432
(Catalog# : 178816, Cas# :
1240308-45-5
)
A‑971432 is highly selective for S1P5 and has excellent plasma and CNS exposure aft
A-1165442
(Catalog# : 20178812, Cas# :
1221443-94-2
)
A-1165442 is a temperature-neutral transient receptor potential vanilloid-1 (TRPV1) a
AZD4205
(Catalog# : 20178710, Cas# :
2091134-35-7
)
AZD4205 is a highly potent JAK1-selective kinase inhibitor with excellent preclinical
ACY-775
(Catalog# : 77821, Cas# :
1375466-18-4
)
ACY-775 is a potent and selective HDAC6 inhbiitor. ACY-775 inhibits HDAC6 with low na
AAI-101
(Catalog# : 1773101, Cas# :
1001404-83-6
)
AAI101(AAI-101) is a novel extended-spectrum -lactamase inhibitor.The combination of
AV-412 Tosylate
(Catalog# : 17030105, Cas# :
451493-31-5
)
AV-412, also known as MP-412, is a second-generation, orally bioavailable dual kinase
AZD-7594
(Catalog# : 17022812, Cas# :
1196509-60-0
)
AZD-7594, also known as AZ13189620, is an inhaled selective glucocorticoid receptor (
ABT888
(Catalog# : 17022801, Cas# :
912445-05-7
)
Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.
AZD3839
(Catalog# : 17022710, Cas# :
1227163-56-5
)
AZD3839 is a potent and selective BACE1 inhibitor. AZD3839 is clinical candidate for
A-1210477
(Catalog# : 17022404, Cas# :
1668553-26-1
)
A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 induces the hallmarks
Apatinib
(Catalog# : 17022301, Cas# :
811803-05-1
)
Apatinib is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM.
Amikacin sulfate
(Catalog# : 17021407, Cas# :
39831-55-5
)
Amikacin sulfate(BAY416651 sulfate) is a semi-synthetic aminoglycoside antibiotic der
AFN-1252
(Catalog# : 17021406, Cas# :
620175-39-5
)
AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (F
AZD3293 (LY3314814)
(Catalog# : 17021318, Cas# :
1383982-64-6
)
AZD3293, also known as LY3314814 is an oral beta-secretase 1 cleaving enzyme (BACE)
APR-246 (PRIMA-1MET)
(Catalog# : 17021316, Cas# :
5291-32-7
)
APR-246, also known as PRIMA-1MET, is a small organic molecule that has been shown to
AZD-8835
(Catalog# : 102703, Cas# :
1620576-64-8
)
AZD8835 is a potent and selective inhibitor of PI3Kalpha and PI3Kdelata with excellen
AZD6482 (S-isomer)
(Catalog# : 17011901, Cas# :
1173900-37-2
)
AZD6482 is a potent, selective and ATP competitive PI3K inhibitor (IC(50) 0.01 μm).
7ACC2
(Catalog# : 17011302, Cas# :
1472624-85-3
)
7ACC2 is a potent MCT inhibitor. Monocarboxylate transporters (MCTs) catalyze the pro
AZD-5597
(Catalog# : 16122865, Cas# :
924641-59-8
)
AZD-5597 is potent CDK inhibitor with in vitro anti-proliferative effects against a r
AZD-5069
(Catalog# : 16122864, Cas# :
878385-84-3
)
AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neu
AZD-2461
(Catalog# : 16122863, Cas# :
1174043-16-3
)
AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. A
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
NVL-655 ( ALK-IN-27 )
(Catalog# : 24003, Cas# :
2739866-40-9
)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add