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Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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Name Index A
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Name Index A
AMD-070 HCl
(Catalog# : 18741, Cas# :
880549-30-4
)
AMD11070, also known as AMD070, X4P-001 and mavorixafor, is an orally bioavailable an
AG-494
(Catalog# : 186273, Cas# :
133550-35-3
)
AG-494, also known as Tyrphostin AG-494, is an inhibitor of epidermal growth factor r
AZD5153
(Catalog# : 186254, Cas# :
1869912-39-9
)
AZD5153 is a potent bivalent triazolopyridazine based Bromodomain and Extraterminal (
Amenamevir
(Catalog# : 186252, Cas# :
841301-32-4
)
Amenamevir, also known as ASP2151, is a herpes virus helicase-primase inhibitor.
A22 hydrochloride
(Catalog# : 186211, Cas# :
22816-60-0
)
A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to a
AST487
(Catalog# : 186158, Cas# :
630124-46-8
)
AST487, also known as NVP- AST487, is a RET kinase inhibitor/FLT3 inhibitor.
ARV-825
(Catalog# : 185253, Cas# :
1818885-28-7
)
ARV-825 is a PROTAC (proteolysis-targeting chimera). ARV-825 exerts superior lethal a
Alobresib
(Catalog# : 185222, Cas# :
1637771-14-2
)
Alobresib is an antineoplastic drug candidate.
Adavivint
(Catalog# : 185221, Cas# :
1467013-03-3
)
Adavivint is a Wnt pathway inhibitor and immunomodulator drug candidate.
ALX 1393
(Catalog# : 185213, Cas# :
949164-09-4
)
ALX 1393 is a glycine transporter-2 inhibitor.
A-485
(Catalog# : 185211, Cas# :
1889279-16-6
)
A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10
AS-1517499
(Catalog# : 185187, Cas# :
919486-40-1
)
AS-1517499 is a potent and selective STAT6 inhibitor.
AMG-176
(Catalog# : 185185, Cas# :
1883727-34-1
)
AMG-176 is an inhibitor of induced myeloid leukemia cell differentiation protein MCL-
A-350619 HCI
(Catalog# : 185183, Cas# :
1217201-17-6
)
A-350619 hydrochloride is an activator of soluble guanylyl cyclase (sGC).
ARQ-531
(Catalog# : 185176, Cas# :
2095393-15-8
)
ARQ-531 is a potent and orally active BTK inhibitor with potential antineoplastic act
ADX-47273
(Catalog# : 185173, Cas# :
851881-60-2
)
ADX-47273 is a potent and selective mGluR5 receptor PAM (positive allosteric modulato
AMG-511
(Catalog# : 18542, Cas# :
1253573-53-3
)
AMG-511 is a potent and selective pan class I PI3K inhibitor.
AZD1390
(Catalog# : 18541, Cas# :
2089288-03-7
)
AZD1390 is a potent and selective ATM inhibitor with the ability to cross the blood-b
ALW-II-41-27
(Catalog# : 1842813, Cas# :
1186206-79-0
)
ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor.
AZD4635
(Catalog# : 184289, Cas# :
1321514-06-0
)
AZD-4635, also known as HTL-1071, is an orally available, small molecule adenosine A2
Acrizanib
(Catalog# : 184181, Cas# :
1229453-99-9
)
Acrizanib, also known as LHA510, is a potent and selective angiogenesis inhibitor and
2-amino-3-methoxy-4-(3-morpholin-4-ylpropoxy)benzonitrile
(Catalog# : 184163, Cas# :
1032570-98-1
)
2-amino-3-methoxy-4-(3-morpholin-4-ylpropoxy)benzonitrile is a drug intermediate.
Anlotinib
(Catalog# : 184132, Cas# :
1058156-90-3
)
Anlotinib, also known as AL3818, is a receptor tyrosine kinase (RTK) inhibitor with p
A-804598
(Catalog# : 184125, Cas# :
1125758-85-1
)
A-804598 is a P2X7 selective, competitive antagonist.
AMD3465 HCl salt
(Catalog# : 184310, Cas# :
185991-07-5
)
AMD3465 is a novel CXCR4 receptor antagonist with potential anticancer and anti-HIV a
Albiglutide
(Catalog# : 18438, Cas# :
782500-75-8
)
Albiglutide is a glucagon-like peptide-1 agonist (GLP-1 agonist).
AVN-492
(Catalog# : 18425, Cas# :
1220646-23-0
)
AVN-492 is a potent and selective 5-HT6R Antagonist. AVN-492 demonstrates good in vit
ALB-127158A
(Catalog# : 18424, Cas# :
1173154-32-9
)
ALB-127158A,又名ALB-127158(a),是治疗肥胖的MCH1拮抗剂。临床前的研
AZD-5904
(Catalog# : 181121, Cas# :
618913-30-7
)
AZD5904 is a potent orally bioavailable MPO inhibitor. In preclinical studies, AZD590
2-Aminopyrimidine-5-carboxylic acid
(Catalog# : 171281, Cas# :
3167-50-8
)
2-Aminopyrimidine-5-carboxylic acid
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran