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PF-05180999

Catalog No: 186153
CAS Number: 1394033-54-5
Purity: >98%

PF-05180999 is a potent and selective PDE2a inhibitor (PDE2a IC50 = 0.001 μM, 2000-fold selective over PDE10) with a reasonable free brain/plasma ratio in rats (0.5).

For research use only. We do not sell to patients.

Chemical Information

NamePF-05180999
Iupac Chemical Name4-(1-Azetidinyl)-7-methyl-5-[1-methyl-5-[5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-4-yl]-imidazo[5,1-f][1,2,4]triazine
SynonymsPF05180999; PF-05180999; PF 5180999; PF5180999; PF-5180999; PF 5180999; PF999; PF-999; PF 999
Molecular FormulaC19H17F3N8
Molecular Weight414.3962
SmileFC(C1=CN=C(C2=C(C3=C4C(N5CCC5)=NC=NN4C(C)=N3)C=NN2C)C=C1)(F)F
InChiKeyCLGCHUKGBICQTE-UHFFFAOYSA-N
InChiInChI=1S/C19H17F3N8/c1-11-27-15(17-18(29-6-3-7-29)24-10-26-30(11)17)13-9-25-28(2)16(13)14-5-4-12(8-23-14)19(20,21)22/h4-5,8-10H,3,6-7H2,1-2H3
CAS Number1394033-54-5
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

186153 - PF-05180999 | CAS 1394033-54-5

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