MDK1846 is a potent ketohexokinase (KHK) inhibitor.
For research use only. We do not sell to patients.
Name | PF-06835919 ( MDK-1846 ) |
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Iupac Chemical Name | 2-((1R,5S,6S)-3-(2-((S)-2-methylazetidin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)bicyclo[3.1.0]hexan-6-yl)acetic acid |
Synonyms | MDK1846 ; MDK-1846 ; MDK 1846 ; ketohexokinase inhibitor ; ketohexokinase-In-1 ; PF-06835919 ; PF06835919 ; PF 06835919 |
Molecular Formula | C17H20F3N3O2 |
Molecular Weight | 355.3612 |
Smile | [H][C@]1(C2)[C@@]([C@@H]1CC(O)=O)([H])CC2C3=NC(N4CC[C@@H]4C)=NC(C(F)(F)F)=C3 |
InChiKey | GPRZURIPQMIXSS-IYJVRESMSA-N |
InChi | InChI=1S/C17H20F3N3O2/c1-8-2-3-23(8)16-21-13(7-14(22-16)17(18,19)20)9-4-10-11(5-9)12(10)6-15(24)25/h7-12H,2-6H2,1H3,(H,24,25)/t8-,9?,10-,11+,12+/m0/s1 |
CAS Number | 2102501-84-6 |
Related CAS | 2102501-84-6 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |