GDD-261
Catalog No: 26A084
CAS Number: 3137699-54-5
Purity: ≧98.0%
GDD-261 is an orally active, allosteric inhibitor of phosphoglycerate dehydrogenase (IC50 = 61 nM), which blocks cellular serine biosynthesis and is studied in cancer metabolism.
For research use only. We do not sell to patients.
Chemical Information
| Name | GDD-261 |
|---|---|
| Iupac Chemical Name | 4-(N-(2-chloro-4-(2,2-difluoroacetamido)phenyl)sulfamoyl)-N-(4-(3-fluorophenyl)thiazol-2-yl)benzamide |
| Synonyms | GDD-261; GDD261; GDD 261 |
| Molecular Formula | C24H16ClF3N4O4S2 |
| Molecular Weight | 581.0 |
| Smile | ClC1=C(NS(C2=CC=C(C(NC3=NC(C4=CC(F)=CC=C4)=CS3)=O)C=C2)(=O)=O)C=CC(NC(C(F)F)=O)=C1 |
| InChiKey | PVAPZZYIYILFPB-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H16ClF3N4O4S2/c25-18-11-16(29-23(34)21(27)28)6-9-19(18)32-38(35,36)17-7-4-13(5-8-17)22(33)31-24-30-20(12-37-24)14-2-1-3-15(26)10-14/h1-12,21,32H,(H,29,34)(H,30,31,33) |
| CAS Number | 3137699-54-5 |
| Related CAS | 3137699-54-5 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
