Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1 and MEK2 kinases.
For research use only. We do not sell to patients.
| Name | Atebimetinib |
|---|---|
| Iupac Chemical Name | 4-[(Dimethylamino)methyl]-3-([2-fluoro-3-[(methylsulfamoyl)amino]phenyl]methyl)-2-oxo-2H-1-benzopyran-7-yl dimethylcarbamate |
| Synonyms | IMM-1-104 ; Atebimetinib ; |
| Molecular Formula | C23H27FN4O6S |
| Molecular Weight | 506.55 |
| Smile | O=C(OC1=CC=C(C(O2)=C1)C(CN(C)C)=C(CC3=CC=CC(NS(=O)(NC)=O)=C3F)C2=O)N(C)C |
| InChiKey | VGDONWMTHHBKMZ-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H27FN4O6S/c1-25-35(31,32)26-19-8-6-7-14(21(19)24)11-17-18(13-27(2)3)16-10-9-15(33-23(30)28(4)5)12-20(16)34-22(17)29/h6-10,12,25-26H,11,13H2,1-5H3 |
| CAS Number | 2669009-92-9 |
| Related CAS | 2669009-92-9 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Light yellow solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | MEK Inhibitor |
|---|---|
| Mechanism | Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1 and MEK2 kinases. |
| Cell study | |
| Animal study | |
| Clinical study | Phase 2a Trial |