Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1 and MEK2 kinases.
For research use only. We do not sell to patients.
Name | Atebimetinib |
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Iupac Chemical Name | 4-[(Dimethylamino)methyl]-3-([2-fluoro-3-[(methylsulfamoyl)amino]phenyl]methyl)-2-oxo-2H-1-benzopyran-7-yl dimethylcarbamate |
Synonyms | IMM-1-104 |
Molecular Formula | C23H27FN4O6S |
Molecular Weight | 506.55 |
Smile | O=C(OC1=CC=C(C(O2)=C1)C(CN(C)C)=C(CC3=CC=CC(NS(=O)(NC)=O)=C3F)C2=O)N(C)C |
InChiKey | VGDONWMTHHBKMZ-UHFFFAOYSA-N |
InChi | InChI=1S/C23H27FN4O6S/c1-25-35(31,32)26-19-8-6-7-14(21(19)24)11-17-18(13-27(2)3)16-10-9-15(33-23(30)28(4)5)12-20(16)34-22(17)29/h6-10,12,25-26H,11,13H2,1-5H3 |
CAS Number | 2669009-92-9 |
Related CAS | 2669009-92-9 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |