PDM-2
Catalog No: 2061301
CAS Number: 688348-25-6
Purity: 98% Min.
PDM-2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM.2 PDM-2 is inactive as a ligand for the estrogen receptor even at 100 µM.
For research use only. We do not sell to patients.
Chemical Information
| Name | PDM-2 |
|---|---|
| Iupac Chemical Name | 1,3-dichloro-5-[(1E)-2-(4-chlorophenyl)ethenyl]-benzene |
| Synonyms | PDM-2; PDM 2; PDM2; |
| Molecular Formula | C14H9Cl3 |
| Molecular Weight | 283.576 |
| Smile | ClC1=CC=C(/C=C/C2=CC(Cl)=CC(Cl)=C2)C=C1 |
| InChiKey | JMYNPQVCVQVODQ-OWOJBTEDSA-N |
| InChi | InChI=1S/C14H9Cl3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9H/b2-1+ |
| CAS Number | 688348-25-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1. Denison, M.S., and Nagy, S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 43, 309-334 (2003).
2. de Medina, P., Casper, R., Savouret, J.F., et al. Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators. Journal of Medicinal Chemistry 48, 287-291 (2005).
Chemical Structure
