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PZ-2891

Catalog No.: 193282
Cas No.: 2170608-82-7
Purity : >98%
193282 - PZ-2891 | CAS 2170608-82-7

Catalog number : 193282

CAS number : 2170608-82-7

Molecular Formula : C20H23N5O

Molecular Weight : 349.438

Iupac Chemical Name : 6-(4-(2-(4-isopropylphenyl)acetyl)piperazin-1-yl)pyridazine-3-carbonitrile

Smile : N#CC1=NN=C(N2CCN(C(CC3=CC=C(C(C)C)C=C3)=O)CC2)C=C1

InChiKey : LGWDVWIZDPGCFG-UHFFFAOYSA-N

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SynonymsPZ-2891; PZ 2891; PZ2891;
Molecular FormulaC20H23N5O
Molecular Weight349.438
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileN#CC1=NN=C(N2CCN(C(CC3=CC=C(C(C)C)C=C3)=O)CC2)C=C1
InChiKeyLGWDVWIZDPGCFG-UHFFFAOYSA-N
InChiInChI=1S/C20H23N5O/c1-15(2)17-5-3-16(4-6-17)13-20(26)25-11-9-24(10-12-25)19-8-7-18(14-21)22-23-19/h3-8,15H,9-13H2,1-2H3
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PZ-2891 is a potent and selective, orally active Pantothenate kinase (PANK) modulator, acting as both an orthosteric inhibitor (IC50=1.3 nM, hPANK3) and an allosteric activator of PANK3 activity in the presence of acetyl-CoA in biochemical assays.

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