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PZ-2891

Catalog No.: 193282
Cas No.: 2170608-82-7
Purity : >98%

PZ-2891 is a potent and selective, orally active Pantothenate kinase (PANK) modulator, acting as both an orthosteric inhibitor (IC50=1.3 nM, hPANK3) and an allosteric activator of PANK3 activity in the presence of acetyl-CoA in biochemical assays.

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Chemical Information

NamePZ-2891
Iupac Chemical Name6-(4-(2-(4-isopropylphenyl)acetyl)piperazin-1-yl)pyridazine-3-carbonitrile
SynonymsPZ-2891; PZ 2891; PZ2891;
Molecular FormulaC20H23N5O
Molecular Weight349.438
SmileN#CC1=NN=C(N2CCN(C(CC3=CC=C(C(C)C)C=C3)=O)CC2)C=C1
InChiKeyLGWDVWIZDPGCFG-UHFFFAOYSA-N
InChiInChI=1S/C20H23N5O/c1-15(2)17-5-3-16(4-6-17)13-20(26)25-11-9-24(10-12-25)19-8-7-18(14-21)22-23-19/h3-8,15H,9-13H2,1-2H3
CAS Number2170608-82-7
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

193282 - PZ-2891 | CAS 2170608-82-7

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