PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC0 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.
For research use only. We do not sell to patients.
Chemical Information
| Name | PF06447475 |
| Iupac Chemical Name | 3-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile |
| Synonyms | PF-06447475; PF 06447475; PF6447475; PF-6447475; PF 6447475 |
| Molecular Formula | C17H15N5O |
| Molecular Weight | 305.33 |
| Smile | N#CC1=CC=CC(C2=CNC3=NC=NC(N4CCOCC4)=C32)=C1 |
| InChiKey | BHTWDJBVZQBRKP-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H15N5O/c18-9-12-2-1-3-13(8-12)14-10-19-16-15(14)17(21-11-20-16)22-4-6-23-7-5-22/h1-3,8,10-11H,4-7H2,(H,19,20,21) |
| CAS Number | 1527473-33-1 |
| Related CAS | |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
| Bulk | | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |