PF-543
Catalog No: 52740
CAS Number: 1415562-82-1
Purity: 98%
PF-543 is a novel cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
For research use only. We do not sell to patients.
Chemical Information
| Name | PF-543 |
|---|---|
| Molecular Formula | C27H31NO4S |
| Molecular Weight | 465.6 |
| Smile | Cc1cc(cc(c1)OCc2ccc(cc2)CN3CCC[C@@H]3CO)CS(=O)(=O)c4ccccc4 |
| InChiKey | NPUXORBZRBIOMQ-RUZDIDTESA-N |
| InChi | InChI=1S/C27H31NO4S/c1-21-14-24(20-33(30,31)27-7-3-2-4-8-27)16-26(15-21)32-19-23-11-9-22(10-12-23)17-28-13-5-6-25(28)18-29/h2-4,7-12,14-16,25,29H,5-6,13,17-20H2,1H3/t25-/m1/s1 |
| CAS Number | 1415562-82-1 |
| MDL | MFCD23098794 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Solubility | DMSO |
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
