PD153035 Hcl is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM; little effect against PGDFR, FGFR, CSF-1, InsR and Src.
For research use only. We do not sell to patients.
Chemical Information
| Name | PD153035 Hcl |
| Iupac Chemical Name | N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride |
| Synonyms | ZM 252868; AG 1517; Tyrphostin AG 1517; SU 5271; PD-153035; PD 153035 |
| Molecular Formula | C16H15BrClN3O2 |
| Molecular Weight | 396.666 |
| Smile | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl |
| InChiKey | ZJOKWAWPAPMNIM-UHFFFAOYSA-N |
| InChi | InChI=1S/C16H14BrN3O2.ClH/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11;/h3-9H,1-2H3,(H,18,19,20);1H |
| CAS Number | 183322-45-4 |
| Related CAS | |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
| Bulk | | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |