PI-3065 is a novel potent and selective PI3K p110 inhibitor with IC50 of 15 nM; exhibits > 100 fold selectivity against p110, p110, p110, DNA-PK and mTOR.
For research use only. We do not sell to patients.
| Name | PI-3065 |
|---|---|
| Iupac Chemical Name | 4-[6-[[4-(cyclopropylmethyl)piperazin-1-yl]methyl]-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin-4-yl]morpholine |
| Synonyms | PI3065; PI 3065 |
| Molecular Formula | C27H31FN6OS |
| Molecular Weight | 506.638 |
| Smile | C1CC1CN2CCN(CC2)CC3=CC4=C(S3)C(=NC(=N4)C5=C(C=CC6=C5C=CN6)F)N7CCOCC7 |
| InChiKey | YDNOHCOYQVZOMC-UHFFFAOYSA-N |
| InChi | InChI=1S/C27H31FN6OS/c28-21-3-4-22-20(5-6-29-22)24(21)26-30-23-15-19(17-33-9-7-32(8-10-33)16-18-1-2-18)36-25(23)27(31-26)34-11-13-35-14-12-34/h3-6,15,18,29H,1-2,7-14,16-17H2 |
| CAS Number | 955977-50-1 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |