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AS-252424

Catalog No.: 160926012
Cas No.: 900515-16-4
Purity : 98% by HPLC 
160926012 - AS-252424 | CAS 900515-16-4

Catalog number : 160926012

CAS number : 900515-16-4

Molecular Formula : C14H8FNO4S 

Molecular Weight : 305.28 

Iupac Chemical Name : (Z)-5-((5-(4-fluoro-2-hydroxyphenyl)furan-2-yl)methylene)thiazolidine-2,4-dione 

Smile : FC1=CC(=C(C=C1)C1=CC=C(O1)\C=C/1\C(NC(S1)=O)=O)O

InChiKey : OYYVWNDMOQPMGE-SDQBBNPISA-N

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SynonymsAS252424; AS 252424; AS-252424. 
Molecular FormulaC14H8FNO4S 
Molecular Weight305.28 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileFC1=CC(=C(C=C1)C1=CC=C(O1)\C=C/1\C(NC(S1)=O)=O)O
InChiKeyOYYVWNDMOQPMGE-SDQBBNPISA-N
InChiInChI=1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6-
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AS-252424 is a potent and selective small-molecule PI3Kgamma inhibitor. Oral administration of AS-252424 in a mouse model of acute peritonitis led to a significant reduction of leukocyte recruitment.  

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