AS-252424 is a potent and selective small-molecule PI3Kgamma inhibitor. Oral administration of AS-252424 in a mouse model of acute peritonitis led to a significant reduction of leukocyte recruitment.
For research use only. We do not sell to patients.
| Name | AS-252424 |
|---|---|
| Iupac Chemical Name | (Z)-5-((5-(4-fluoro-2-hydroxyphenyl)furan-2-yl)methylene)thiazolidine-2,4-dione |
| Synonyms | AS252424; AS 252424; AS-252424. |
| Molecular Formula | C14H8FNO4S |
| Molecular Weight | 305.28 |
| Smile | FC1=CC(=C(C=C1)C1=CC=C(O1)\C=C/1\C(NC(S1)=O)=O)O |
| InChiKey | OYYVWNDMOQPMGE-SDQBBNPISA-N |
| InChi | InChI=1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6- |
| CAS Number | 900515-16-4 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |