Pantothenate kinase-IN-2
Catalog No: 26A038
CAS Number: 902614-04-4
Purity: ≧98.0%
Pantothenate kinase-IN-2 is a pantothenate kinase inhibitor with IC50 values of 92 nM for PanK2, 70 nM for PanK1β, and 25 nM for PanK3. Pantothenate kinase-IN-2 can bind specifically to the ATP-PanK3 complex and block CoA biosynthesis. Pantothenate kinase-IN-2 can be used for the research of pank-associated neurodegeneration and type 2 diabetes.
For research use only. We do not sell to patients.
Chemical Information
| Name | Pantothenate kinase-IN-2 |
|---|---|
| Iupac Chemical Name | 3-(2,4-dimethylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-3-yl)-N-(3-(methylthio)phenyl)propanamide |
| Synonyms | Pantothenate kinase-IN-2 |
| Molecular Formula | C21H21N5OS |
| Molecular Weight | 391.1 |
| Smile | O=C(NC1=CC=CC(SC)=C1)CCC2=C(C)N3N=C4N=CC=CC4=C3N=C2C |
| InChiKey | UNCZUEUPSJKHGB-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H21N5OS/c1-13-17(9-10-19(27)24-15-6-4-7-16(12-15)28-3)14(2)26-21(23-13)18-8-5-11-22-20(18)25-26/h4-8,11-12H,9-10H2,1-3H3,(H,24,27) |
| CAS Number | 902614-04-4 |
| Related CAS | 902614-04-4 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
