Avasopasem manganese (GC-4419; M-40419)
Catalog No: 25108
CAS Number: 435327-40-5
Purity: ≧97.0%
Avasopasem manganese, also known as GC-4419; M 40419 and SC-72325A, is a mimetic of the enzyme superoxide dismutase (SOD) that may potentially be used to reduce oral mucositis and esophagitis associated with radiation therapy and chemoradiotherapy. Upon administration, avasopasem manganese may mimic native SODs and catalyze the formation of molecular oxygen and hydrogen peroxide from the burst of superoxide anion present in the irradiated tissues upon radiation and/or induced by chemotherapy. This may decrease the damage of radiation and/or chemotherapy to normal tissues.
For research use only. We do not sell to patients.
Chemical Information
| Name | Avasopasem manganese (GC-4419; M-40419) |
|---|---|
| Iupac Chemical Name | (PBPY-7-11-2344'3')-dichlorido[(11S,12S,71S,72S)-2,6,8,11-tetraaza-4(2,6)-pyridina-1,7(1,2)-dicyclohexanacycloundecaphane-κ5N2,N1.4,N6,N8,N11]manganese |
| Synonyms | Avasopasem manganese; GC-4419; GC4419; GC 4419; M 40419; M40419; M-40419; SC 72325A; SC-72325A; SC72325A; |
| Molecular Formula | C21H35Cl2MnN5 |
| Molecular Weight | 483.38 |
| Smile | Cl[Mn-5]1234(Cl)[N@@H+]([C@H]5CCCC[C@@H]5[N@H+]2CC6=CC=CC7=[N+]63)CC[N@@H+]1[C@@H]8[C@@H]([N@H+]4C7)CCCC8 |
| InChiKey | WXEMWBBXVXHEPU-NDOCQCNASA-L |
| InChi | InChI=1S/C21H35N5.2ClH.Mn/c1-3-10-20-18(8-1)22-12-13-23-19-9-2-4-11-21(19)25-15-17-7-5-6-16(26-17)14-24-20;;;/h5-7,18-25H,1-4,8-15H2;2*1H;/q;;;+2/p-2/t18-,19-,20-,21-;;;/m0.../s1 |
| CAS Number | 435327-40-5 |
| Related CAS | 435327-40-5 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧97.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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