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AS-605240 Catalog No : 160926007

Chemical Information

Product NameAS-605240
Iupac Chemical Name(E)-5-(quinoxalin-6-ylmethylene)thiazolidine-2,4-dione 
SynonymsAS 605240; AS605240; AS-605240. 
Molecular FormulaC12H7N3O2S 
Molecular Weight257.27 
SmileN1=CC=NC2=CC(=CC=C12)\C=C\1/C(NC(S1)=O)=O
InChiKeySQWZFLMPDUSYGV-UXBLZVDNSA-N
InChiInChI=1S/C12H7N3O2S/c16-11-10(18-12(17)15-11)6-7-1-2-8-9(5-7)14-4-3-13-8/h1-6H,(H,15,16,17)/b10-6+
Cas648450-29-7

Technical Data

AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Orally administration of AS605240 significantly prevented lung inflammation and reduced collagen deposition. AS605240 also inhibited augmented expression of TNF-alpha and IL-1beta induced by bleomycin instillation. AS605240 may be a useful in treating inflammation diseases. AS605240 may represent a promising novel agent for the future therapy of pulmonary fibrosis.  

Chemical Structure

160926007 - AS-605240 | CAS 648450-29-7

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