+86-27-65522453 sales@sun-shinechem.com


Catalog No.: 16071413
Cas No.: 870281-34-8
Purity : 98% by HPLC 
16071413 - Acalisib | CAS 870281-34-8

Catalog number : 16071413

CAS number : 870281-34-8

Molecular Formula : C21H16FN7O 

Molecular Weight : 401.4 

Iupac Chemical Name : (S)-2-(1-((7H-purin-6-yl)amino)ethyl)-6-fluoro-3-phenylquinazolin-4(3H)-one 

Smile : N1=CN=C2N=CNC2=C1N[C@@H](C)C1=NC2=CC=C(C=C2C(N1C1=CC=CC=C1)=O)F


PackagingPriceAvailabilityPurityEstimated Shipping Time
Request Bulk Quote Download MSDSTel:+86-27-65522453 | Email:sales@sun-shinechem.com
SynonymsGS-9820; GS9820 
Molecular FormulaC21H16FN7O 
Molecular Weight401.4 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Coming soon.

Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide-3 kinases (PI3K) with potential immunomodulating and antineoplastic activities. p110beta/delta PI3K inhibitor GS-9820 inhibits the activity of PI3K, thereby preventing the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3), which decreases tumor cell proliferation and induces cell death. PI3K-mediated signaling is often dysregulated in cancer cells; the targeted inhibition of PI3K is designed to preserve PI3K signaling in normal, non-neoplastic cells. Check for active clinical trials or closed clinical trials using this agent. 

870281-34-8 - Request Bulk Quote

870281-34-8 - Request Bulk Quote