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AT7867 Catalog No : 161009021

Chemical Information

Product NameAT7867
Iupac Chemical Name4-(4-(1H-pyrazol-4-yl)phenyl)-4-(4-chlorophenyl)piperidine 
SynonymsAT7867; AT 7867; AT-7867; AT7867 HCl; AT7867 dihydrochloride. AT7867 hydrochloride. 
Molecular FormulaC20H20ClN3 
Molecular Weight337.8459 
SmileN1N=CC(=C1)C1=CC=C(C=C1)C1(CCNCC1)C1=CC=C(C=C1)Cl
InChiKeyLZMOSYUFVYJEPY-UHFFFAOYSA-N
InChiInChI=1S/C20H20ClN3/c21-19-7-5-18(6-8-19)20(9-11-22-12-10-20)17-3-1-15(2-4-17)16-13-23-24-14-16/h1-8,13-14,22H,9-12H2,(H,23,24)
Cas857531-00-1 (free base); 1431697-86-7 (2HCl)

Technical Data

AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

This ATP-competitive small molecule potently inhibits both AKT and p70S6K activity at the cellular level, as measured by inhibition of GSK3beta and S6 ribosomal protein phosphorylation, and also causes growth inhibition in a range of human cancer cell lines as a single agent. 

Chemical Structure

161009021 - AT7867 | CAS 857531-00-1 (free base); 1431697-86-7 (2HCl)

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