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AT7867

Catalog No.: 161009021
Cas No.: 857531-00-1 (free base); 1431697-86-7 (2HCl)
Purity : 98% by HPLC 
161009021 - AT7867 | CAS 857531-00-1 (free base); 1431697-86-7 (2HCl)

Catalog number : 161009021

CAS number : 857531-00-1 (free base); 1431697-86-7 (2HCl)

Molecular Formula : C20H20ClN3 

Molecular Weight : 337.8459 

Iupac Chemical Name : 4-(4-(1H-pyrazol-4-yl)phenyl)-4-(4-chlorophenyl)piperidine 

Smile : N1N=CC(=C1)C1=CC=C(C=C1)C1(CCNCC1)C1=CC=C(C=C1)Cl

InChiKey : LZMOSYUFVYJEPY-UHFFFAOYSA-N

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SynonymsAT7867; AT 7867; AT-7867; AT7867 HCl; AT7867 dihydrochloride. AT7867 hydrochloride. 
Molecular FormulaC20H20ClN3 
Molecular Weight337.8459 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileN1N=CC(=C1)C1=CC=C(C=C1)C1(CCNCC1)C1=CC=C(C=C1)Cl
InChiKeyLZMOSYUFVYJEPY-UHFFFAOYSA-N
InChiInChI=1S/C20H20ClN3/c21-19-7-5-18(6-8-19)20(9-11-22-12-10-20)17-3-1-15(2-4-17)16-13-23-24-14-16/h1-8,13-14,22H,9-12H2,(H,23,24)
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This ATP-competitive small molecule potently inhibits both AKT and p70S6K activity at the cellular level, as measured by inhibition of GSK3beta and S6 ribosomal protein phosphorylation, and also causes growth inhibition in a range of human cancer cell lines as a single agent. 

857531-00-1 (free base); 1431697-86-7 (2HCl) - Request Bulk Quote

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