AMG 517 is a potent and selective TRPV1 antagonist, and antagonizes capsaicin, proton, and heat activation of TRPV1.
For research use only. We do not sell to patients.
Chemical Information
| Name | AMG-517 |
| Iupac Chemical Name | Acetamide, N-(4-((6-(4-(trifluoromethyl)phenyl)-4-pyrimidinyl)oxy)-2-benzothiazolyl)- |
| Synonyms | AMG-517; AMG 517 |
| Molecular Formula | C20H13F3N4O2S |
| Molecular Weight | 430.4 |
| Smile | FC(C1=CC=C(C=C1)C1=CC(=NC=N1)OC1=CC=CC2=C1N=C(S2)NC(C)=O)(F)F |
| InChiKey | YUTIXVXZQIQWGY-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H13F3N4O2S/c1-11(28)26-19-27-18-15(3-2-4-16(18)30-19)29-17-9-14(24-10-25-17)12-5-7-13(8-6-12)20(21,22)23/h2-10H,1H3,(H,26,27,28) |
| CAS Number | 659730-32-2 |
| Related CAS | |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
| Bulk | | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |