AKT inhibitor VIII
Catalog No: 161009020
CAS Number: 612847-09-3
Purity: 98% by HPLC
AKT inhibitor VIII suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells. AKT inhibitor VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium/calmodulin-dependent protein kinase 1 and smooth muscle myosin light-chain kinase.
For research use only. We do not sell to patients.
Chemical Information
| Name | AKT inhibitor VIII |
|---|---|
| Iupac Chemical Name | 3-[1-[[4-(7-phenyl-3H-imidazo[4,5-g]quinoxalin-6-yl)phenyl]methyl]piperidin-4-yl]-1H-benzimidazol-2-one |
| Synonyms | AKT inhibitor VIII; AKT-inhibitor-VIII; AKT inhibitor-8; AKT-inhibitor-8; Akt-I 1,2; Akti-1/2. Sigma-A6730 |
| Molecular Formula | C34H29N7O |
| Molecular Weight | 551.65 |
| Smile | C1(=CC=CC=C1)C=1C(=NC=2C=C3C(=CC2N1)N=CN3)C3=CC=C(C=C3)CN3CCC(CC3)N3C(NC1=C3C=CC=C1)=O |
| InChiKey | BIWGYFZAEWGBAL-UHFFFAOYSA-N |
| InChi | InChI=1S/C34H29N7O/c42-34-39-26-8-4-5-9-31(26)41(34)25-14-16-40(17-15-25)20-22-10-12-24(13-11-22)33-32(23-6-2-1-3-7-23)37-29-18-27-28(36-21-35-27)19-30(29)38-33/h1-13,18-19,21,25H,14-17,20H2,(H,35,36)(H,39,42) |
| CAS Number | 612847-09-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
