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抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
Services
Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
Services
Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
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Name Index P
PIK-93
(Catalog# : 160926009, Cas# :
593960-11-3
)
PIK-93 is a potent PI3K inhibitor. PIK93 selectively inhibits the type III PI 4-kinas
PI-103
(Catalog# : 160926002, Cas# :
371935-74-9
)
It inhibits ATR and ATM only at much higher concentrations (IC50= 850 and 920 nM, res
PNU-159682
(Catalog# : 16071409, Cas# :
202350-68-3
)
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsom
Pevonedistat
(Catalog# : 16071408, Cas# :
905579-51-3
)
Pevonedistat, also known as MLN-4924 and TAK-924, is a small molecule inhibitor of Ne
PRX-08066
(Catalog# : 16071114, Cas# :
866206-54-4
)
PRX-08066 is a a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotal
PS 48
(Catalog# : 16071111, Cas# :
1180676-32-7
)
PS 48 has been shown to be a PKB Kinase (phosphoinositide-dependent protein kinase-1,
Panulisib
(Catalog# : 16071030, Cas# :
1356033-60-7
)
Panulisib, also known as AK151761, is a potent and selective imidazoquinoline based P
Piclidenoson
(Catalog# : 16071028, Cas# :
152918-18-8
)
Piclidenoson, also known as CF101, is a specific agonist to the A3 adenosine receptor
Pirarubicin
(Catalog# : 16070806, Cas# :
72496-41-4
)
Pirarubicin is an anthracycline drug. An analogue of the anthracycline antineoplastic
PS47
(Catalog# : 16070703, Cas# :
1180676-33-8
)
PS47
PIK-293
(Catalog# : 16062804, Cas# :
900185-01-5
)
PIK-293 is a PI3K inhibitor
5-pyridin-4-yl-2,4-dihydro-3H-1,2,4-triazole-3-thione
(Catalog# : 16062108, Cas# :
1477-24-3
)
5-PYRIDIN-4-YL-4H-[1,2,4]TRIAZOLE-3-THIOL
Paritaprevir
(Catalog# : 16060702, Cas# :
1216941-48-8
)
Paritaprevir, also known as ABT-450, is an acylsulfonamide inhibitor of the NS3-4A se
PXD-101
(Catalog# : 16053002, Cas# :
866323-14-0
)
Belinostat (trade name Beleodaq, previously known as PXD101) is a histone deacetylase
PS-1145
(Catalog# : 032501, Cas# :
431898-65-6
)
Coming soon!
2-Pyridinemethanamine, N-[2-(diphenylphosphino)ethyl]-
(Catalog# : 032407, Cas# :
1388712-98-8
)
Coming soon!
PF-06424439
(Catalog# : 020202, Cas# :
1469284-78-3
)
PF-06424439 is a potent and selective Diacylglycerol Acyltransferase 2 ( DGAT2) inhib
PF-06471553
(Catalog# : 020201, Cas# :
1808094-07-6
)
PF-06471553 is a potent and selective Monoacylglycerol acyltransferase 3 (MGAT3) inhi
PF-06282999
(Catalog# : 020102, Cas# :
1435467-37-0
)
PF-06282999 is an irreversible inactivator of myeloperoxidase, and currently in clini
PF-3274167
(Catalog# : 020101, Cas# :
900510-03-4
)
PF-3274167 is a high-affinity nonpeptide oxytocin receptor (OTR) antagonist, with Ki
Pifithrin-alpha
(Catalog# : 012011, Cas# :
63208-82-2
)
Pifithrin- is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-re
PF-04880594
(Catalog# : 012008, Cas# :
1111636-35-1
)
PF-04880594 is a RAF inhibitor, which induces ERK phosphorylation and RAF dimerizatio
PF-2545920
(Catalog# : 012006, Cas# :
898562-94-2
)
PF-2545920 is a phosphodiesterase inhibitor selective for the PDE10A subtype, which i
Pyriofenone
(Catalog# : 011119, Cas# :
688046-61-9
)
Coming soon!
PF-03814735
(Catalog# : 011105, Cas# :
942487-16-3
)
PF-03814735 is an orally bioavailable, ATP-competitive, reversible small-molecule Aur
PND-1186
(Catalog# : 010821, Cas# :
1061353-68-1
)
PND-1186 is a potent FAK inhibitor with a 50% inhibitory concentration of 1.5 nM in v
PF-04217903
(Catalog# : 010807, Cas# :
956905-27-4
)
PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susce
PF-5274857
(Catalog# : 010423, Cas# :
1373615-35-0
)
PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (
Pravadoline
(Catalog# : 010415, Cas# :
92623-83-1
)
Coming soon!
PD318088
(Catalog# : 010414, Cas# :
391210-00-7
)
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binds simultaneously w
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Products Catalog
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
Latest Products
Temozolomide
(Catalog# : 25209, Cas# :
85622-93-1
)
替莫唑胺是一种烷化剂。
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,
Opakalim
(Catalog# : 25193, Cas# :
2376397-93-0
)
Opakalim(BHV-7000)是Kv7.2/7.3钾通道(KCNQ2/3)的口服小分子激活剂,
PF-06835919 ( MDK-1846 )
(Catalog# : 193264, Cas# :
2102501-84-6
)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
MK256
(Catalog# : 25208, Cas# :
2271348-04-8
)
MK256是一种新型CDK8抑制剂,通过下调STAT通路在急性髓系白血病(
NSD1 抑制剂 BT5
(Catalog# : 25207, Cas# :
2351225-46-0
)
BT5可有效抑制NSD1,与细胞中的SET结构域结合,并降低H3K36me2水平。
MA242 TFA
(Catalog# : 25206, Cas# :
1049704-18-8
)
MA242是一种MDM2和NFAT1双重抑制剂,可诱导MDM2自泛素化及降解,并抑
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 )是一种口服选择性成纤维细胞生长因子受体3(
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B 是一种高效、选择性变构 M1 毒蕈碱和 σ1 受体激动剂。 AF710
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A抑制剂5具有抑制MAT2A的高效力和对MTAP缺失的癌症细胞系的显著