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• PLX-4720 (Catalog# : 52592, Cas# : 918505-84-7)PLX 4720 is a potent and selective inhibitor of B-RafV600E(IC50=13 nM) and c-Raf-1Y34
• Palomid 529 (Catalog# : 52591, Cas# : 914913-88-5)Palomid 529 (P529) is a novel potent inhibitor of both the mTORC1 and mTORC2 complexe
• PHT-427 (Catalog# : 52583, Cas# : 1191951-57-1)PHT-427 is a dual Akt and PDPK1 inhibitor (high affinity binding for the PH domains o
• Purvalanol A (Catalog# : 52564, Cas# : 212844-53-6)Purvalanol A(NG-60) is a potent, cell-permeable, and selective inhibitor of cyclin-de
• PI3K-IN-1 (Catalog# : 52560, Cas# : 1349796-36-6)PI3K-IN-1 is a potent inhibitor of PI3K, more information can be found in patent WO20
• Purvalanol B (Catalog# : 52559, Cas# : 212844-54-7)Purvalanol B(NG-95) is a cyclin-dependent kinase inhibitor with IC50 values of 6, 6,
• Pracinostat (Catalog# : 52552, Cas# : 929016-96-6)Pracinostat(SB939) is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with excepti
• Purmorphamine (Catalog# : 52519, Cas# : 483367-10-8)Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopami
• PD 169316 (Catalog# : 52513, Cas# : 152121-53-4)PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor (IC50 =
• PD153035 (Catalog# : 52223, Cas# : 153436-54-5)PD153035(ZM 252868; AG 1517) is a potent and specific inhibitor of EGFR with Ki and I
• PPQ-102 (Catalog# : 52233, Cas# : 931706-15-9)PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride curre
• PTC124c (Catalog# : 52231, Cas# : 775304-57-9)PTC124 (Ataluren) selectively induces ribosomal read-through of premature but not nor
• PR-619 (Catalog# : 52227, Cas# : 2645-32-1)PR-619 is a broad-range DUB inhibitor with potential for further development as a che
• PFI-2 (Catalog# : 52113, Cas# : 1627676-59-8)PFI-2 is a potent, selective, and cell-activelysine methyltransferase SETD7inhibitor
• Ponatinib (AP24534) (Catalog# : 52107, Cas# : 943319-70-8)Ponatinib (AP24534) is a novel, potent multi-target inhibitor ofAbl, PDGFR, VEGFR2, F
• Palbociclib (Catalog# : 52001, Cas# : 571190-30-2)Palbociclib (PD-0332991) is an orally available pyridopyrimidine-derived cyclin-depen
• Palbociclib(PD-0332991)HCl (Catalog# : 52011, Cas# : 827022-32-2)Palbociclib (PD-0332991) HCl is a highly selective inhibitor ofCDK4/6withIC50of 11 nM
• Palbociclib (PD0332991) Isethionate (Catalog# : 52012, Cas# : 827022-33-3)Palbociclib (PD0332991) Isethionate is a highly selective inhibitor ofCDK4/6withIC50o
• PF-06463922 (Catalog# : 51701, Cas# : 1454846-35-5)PF-06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosin