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抑制剂/受体激动剂
Angiogenesis
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Apoptosis
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JAK/STAT
MAPK
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分子砌块
Aldehydes
Amines
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Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
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Deuterated
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
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产品名字索引 P
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产品名字索引 P
培利替尼
(Catalog# : 17022702, Cas# :
257933-82-7
)
培利替尼(EKB-569; WAY-EKB 569)是一种有效且不可逆转的IC50为38.5 nM的E
PCI-34051
(Catalog# : 17022402, Cas# :
950762-95-5
)
PCI-34051是一种有效的组蛋白去乙酰化酶8(HDAC8)特异性抑制剂,在其
补骨脂素
(Catalog# : 17021307, Cas# :
66-97-7
)
补骨脂素是一种自然发生的与DNA相互作用的补骨脂素,抑制DNA合成
P7C3-A20
(Catalog# : 16122838, Cas# :
1235481-90-9
)
P7C3-A20 is an analogue of P7C3, and is a proneurogenic, neuroprotective agent. P7C3-
P7C3
(Catalog# : 16122837, Cas# :
301353-96-8
)
P7C3 is a proneurogenic, neuroprotective agent. P7C3 protects newborn neurons from ap
3PO
(Catalog# : 161227109, Cas# :
13309-08-5
)
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO
P5091 (P005091)
(Catalog# : 16122795, Cas# :
882257-11-6
)
P5091(P005091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (
PYR-41
(Catalog# : 16122793, Cas# :
418805-02-4
)
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with
PRI-724
(Catalog# : 16122785, Cas# :
847591-62-2
)
PRI-724 is a potent, specific inhibitor of the canonical Wnt signaling pathway in can
PLX7904
(Catalog# : 16122777, Cas# :
1393465-84-3
)
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor.
Pamapimod (R-1503, Ro4402257)
(Catalog# : 16122774, Cas# :
449811-01-2
)
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activate
PRIMA-1
(Catalog# : 16122770, Cas# :
5608-24-2
)
PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of huma
Picolinamide
(Catalog# : 16122714, Cas# :
1452-77-3
)
Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuc
PD0166285
(Catalog# : 16122710, Cas# :
185039-89-8
)
PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentratio
Peficitinib (ASP015K, JNJ-54781532)
(Catalog# : 16122707, Cas# :
944118-01-8
)
Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.
PF-543 Citrate
(Catalog# : 6111525, Cas# :
1415562-83-2
)
PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-
Pasireotide
(Catalog# : 61115, Cas# :
396091-73-9
)
Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits un
PFI-3
(Catalog# : 6111020, Cas# :
1819363-80-8
)
PFI-3
PF-2771
(Catalog# : 611943)
PF-2771 is a potent, selective CENP-E inhibitor, PF-2771 inhibits CENP-E motor activi
PF-04929113 Mesylate
(Catalog# : 611939, Cas# :
1173111-67-5
)
PF-04929113 Mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median
PI4KIIIbeta-IN-9
(Catalog# : 611908, Cas# :
1429624-84-9
)
PI4KIII-IN-9 is a potent PI4KIII inhibitor (IC50 of 7 nM) and is >140-fold selecti
PI4KIIIbeta-IN-10
(Catalog# : 611907, Cas# :
1881233-39-1
)
PI4KIIIbeta-IN-10 is the most potent PI4KIII inhibitor currently reported, with very
PI3Kα inhibitor 1
(Catalog# : 611903, Cas# :
1235449-52-1
)
PI3Kα inhibitor 1 is a PI3Kα inhibitor extracted from patent US/20120088764A1, comp
PF-04979064
(Catalog# : 611902, Cas# :
1220699-06-8
)
PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50)
PQR620
(Catalog# : 611821, Cas# :
1927857-56-4
)
PRQ620 is a highly potent and selective mTORC1/2 inhibitor, shows anti-tumor effects
PP121
(Catalog# : 161009011, Cas# :
1092788-83-4
)
PP121 blocks the proliferation of tumor cells by direct inhibition of oncogenic tyros
PF-4989216
(Catalog# : 161009002, Cas# :
1276553-09-3
)
PF-4989216 inhibits the phosphorylation of PI3K downstream molecules and subsequently
PIK-294
(Catalog# : 160926013, Cas# :
900185-02-6
)
PIK-294 is a highly selective inihibitor of the phosphoinositide 3-kinase (PI3K) p110
PIK-90
(Catalog# : 160926010, Cas# :
677338-12-4
)
PIK-90 is a potent PI3K inhibitor with potential anticancer activity.
PIK-93
(Catalog# : 160926009, Cas# :
593960-11-3
)
PIK-93 is a potent PI3K inhibitor. PIK93 selectively inhibits the type III PI 4-kinas
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Dencatistat
(Catalog# : 25177, Cas# :
2377000-84-3
)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
DS-1001b
(Catalog# : 25178, Cas# :
1898207-64-1
)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
Z57346765
(Catalog# : 25191, Cas# :
1016340-64-9
)
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes
CBR-470-1
(Catalog# : 25192, Cas# :
2416095-06-0
)
CBR-470-1 is an Inhibitor of the glycolytic enzyme PGK1that induces Nrf2 activity.
Safusidenib
(Catalog# : 25149, Cas# :
1898206-17-1
)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
HC-7366
(Catalog# : 25076, Cas# :
2803470-63-3
)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
Flavopiridol ( Alvocidib )
(Catalog# : 237071, Cas# :
146426-40-6
)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
AG-270
(Catalog# : 25176, Cas# :
2201056-66-6
)
MAT2A Inhibitor AG-270 is an orally available small molecule inhibitor of methionine
AZD-5904
(Catalog# : 181121, Cas# :
618913-30-7
)
AZD5904 is a potent orally bioavailable MPO inhibitor. In preclinical studies, AZD590
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa