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抑制剂/受体激动剂
Angiogenesis
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Aldehydes
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Amino Acids
Anilines
Boronic Acids
Bromides
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Deuterated
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
Nuclear Receptor
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
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Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 P
PD-161570
(Catalog# : 17030304, Cas# :
192705-80-9
)
PD - 161570是一种选择性FGFR抑制剂(FGFR、PDGFR和EGFR的IC50值分别为40,2
PF-06273340
(Catalog# : 17030201, Cas# :
1402438-74-7
)
PF-06273340是一种有效的、选择性的、具有良好效果的LipE剖面的Pan-
PF-8380
(Catalog# : 17030115, Cas# :
1144035-53-9
)
PF-8380是一种有效的自动分类抑制剂,在分离的酶测定中的IC(50)有
普可那利
(Catalog# : 17030111, Cas# :
153168-05-9
)
普可那利是一种抗病毒药物,可能用于治疗肠病毒感染和哮喘。
帕比司他
(Catalog# : 17022809, Cas# :
404950-80-7
)
帕比司他(LBH-589)是一种广谱HDAC抑制剂;低纳米分子浓度(IC50 =5-20 nM
培利替尼
(Catalog# : 17022702, Cas# :
257933-82-7
)
培利替尼(EKB-569; WAY-EKB 569)是一种有效且不可逆转的IC50为38.5 nM的E
PCI-34051
(Catalog# : 17022402, Cas# :
950762-95-5
)
PCI-34051是一种有效的组蛋白去乙酰化酶8(HDAC8)特异性抑制剂,在其
补骨脂素
(Catalog# : 17021307, Cas# :
66-97-7
)
补骨脂素是一种自然发生的与DNA相互作用的补骨脂素,抑制DNA合成
P7C3-A20
(Catalog# : 16122838, Cas# :
1235481-90-9
)
P7C3-A20 is an analogue of P7C3, and is a proneurogenic, neuroprotective agent. P7C3-
P7C3
(Catalog# : 16122837, Cas# :
301353-96-8
)
P7C3 is a proneurogenic, neuroprotective agent. P7C3 protects newborn neurons from ap
3PO
(Catalog# : 161227109, Cas# :
13309-08-5
)
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO
P5091 (P005091)
(Catalog# : 16122795, Cas# :
882257-11-6
)
P5091(P005091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (
PYR-41
(Catalog# : 16122793, Cas# :
418805-02-4
)
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with
PRI-724
(Catalog# : 16122785, Cas# :
847591-62-2
)
PRI-724 is a potent, specific inhibitor of the canonical Wnt signaling pathway in can
PLX7904
(Catalog# : 16122777, Cas# :
1393465-84-3
)
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor.
Pamapimod (R-1503, Ro4402257)
(Catalog# : 16122774, Cas# :
449811-01-2
)
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activate
PRIMA-1
(Catalog# : 16122770, Cas# :
5608-24-2
)
PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of huma
Picolinamide
(Catalog# : 16122714, Cas# :
1452-77-3
)
Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuc
PD0166285
(Catalog# : 16122710, Cas# :
185039-89-8
)
PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentratio
Peficitinib (ASP015K, JNJ-54781532)
(Catalog# : 16122707, Cas# :
944118-01-8
)
Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.
PF-543 Citrate
(Catalog# : 6111525, Cas# :
1415562-83-2
)
PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-
Pasireotide
(Catalog# : 61115, Cas# :
396091-73-9
)
Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits un
PFI-3
(Catalog# : 6111020, Cas# :
1819363-80-8
)
PFI-3
PF-2771
(Catalog# : 611943)
PF-2771 is a potent, selective CENP-E inhibitor, PF-2771 inhibits CENP-E motor activi
PF-04929113 Mesylate
(Catalog# : 611939, Cas# :
1173111-67-5
)
PF-04929113 Mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median
PI4KIIIbeta-IN-9
(Catalog# : 611908, Cas# :
1429624-84-9
)
PI4KIII-IN-9 is a potent PI4KIII inhibitor (IC50 of 7 nM) and is >140-fold selecti
PI4KIIIbeta-IN-10
(Catalog# : 611907, Cas# :
1881233-39-1
)
PI4KIIIbeta-IN-10 is the most potent PI4KIII inhibitor currently reported, with very
PI3Kα inhibitor 1
(Catalog# : 611903, Cas# :
1235449-52-1
)
PI3Kα inhibitor 1 is a PI3Kα inhibitor extracted from patent US/20120088764A1, comp
PF-04979064
(Catalog# : 611902, Cas# :
1220699-06-8
)
PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50)
PQR620
(Catalog# : 611821, Cas# :
1927857-56-4
)
PRQ620 is a highly potent and selective mTORC1/2 inhibitor, shows anti-tumor effects
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
----
SSTR
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
----
Hemoglobin
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Linafexor (别名: CS-0159)
(Catalog# : 26A089, Cas# :
2765593-43-7
)
Linafexor(同义词:CS-0159)是法尼醇X受体(FXR)的强效非胆汁酸激
Prifetrastat (Synonyms: PF-07248144)
(Catalog# : 26A088, Cas# :
2569008-99-5
)
Prifetrastat (Synonyms: PF-07248144) 是一款首创、选择性、口服活性的
Camonsertib
(Catalog# : 24052, Cas# :
2417489-10-0
)
Camonsertib,也称为RP 3500,是一种新型、强效和选择性的ATR抑制剂,
MRX-2843
(Catalog# : 26A087, Cas# :
1429882-07-4
)
MRX-2843 是一种口服可用的双受体酪氨酸激酶(RTKs)抑制剂,作用
GDC-0134
(Catalog# : 20432, Cas# :
1637394-01-4
)
GDC-0134是一种MAP3K12(DLK)抑制剂。
BI-847325
(Catalog# : 25046, Cas# :
2128698-24-6
)
BI-847325是一种新型的、可口服的、竞争ATP结合位点的Aurora激酶和M
GDD-261
(Catalog# : 26A084, Cas# :
3137699-54-5
)
GDD-261是一种口服活性的磷酸甘油酸脱氢酶变构抑制剂(IC50=61nM)
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib(IMM-1-104)是一种口服的小分子MEK1和MEK2激酶变构抑制剂
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。