优势产品

• Netarsudil(Mesylate) (Netarsudil(Mesylate)) (Catalog# : 712181, Cas# : 1422144-42-0) NEWNetarsudil( AR-11324) is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and​/or reducing intraocular pressure. Netarsudil Increas
• 恩曲替尼 (Entrectinib(RXDX-101)) (Catalog# : 100504, Cas# : 1108743-60-7) Entrectinib (RXDX-101) is a selective inhibitor for all three TRK receptor tyrosine kinases encoded by the three NTRK genes, as well as the ROS1 and ALK receptor tyrosine kinases.
• JPH203 HCl (JPH203 HCl) (Catalog# : 18381, Cas# : 1597402-27-1) JPH203,也称为KYT- 0353,是一个强有力的和选择性(l型氨基酸转运蛋白1)的LAT1选择性抑制剂。JPH203可以很有说服力地抑制l-leucine吸收。
• lumateperone(Tosylate) (lumateperone(Tosylate)) (Catalog# : 17012102, Cas# : 1187020-80-9) Lumateperone (ITI-722/ITI-007)是一种新型的双5HT2A受体拮抗剂/多巴胺磷蛋白调制器(DPPM)，用于精神分裂症。
• SCR7 pyrazine (SCR7 pyrazine) (Catalog# : 1712261, Cas# : 14892-97-8) NEWSCR7吡嗪是DNA连接酶IV的小分子抑制剂,防止非同源端连接通过干扰连接酶结合和激活细胞凋亡。
• eCF506 (eCF506 ) (Catalog# : 18382, Cas# : 1914078-41-3) eCF506靶向一种叫做Src酪氨酸激酶的分子，这是乳腺癌细胞生长和传播所必需的。eCF506可能对阻止乳腺癌细胞的生长非常有效。
• Esaxerenone (Esaxerenone) (Catalog# : 1710121, Cas# : 1632006-28-0) Esaxerenone（cs-3150，xl-550）是一种非甾体类抗盐皮质激素Exelixis发现的，现在由Daiichi Sankyo公司发展为高血压，治疗高血压病，醛固酮增多症和糖尿病肾病。它作为一个具有高度选择性的沉默拮抗盐皮质激素受体（MR）、醛固酮受体，大于1000倍的选择性受体在其他类固醇激素的受体，并对MR相对于现有的antiminera
• Copanlisib HCl (Copanlisib HCI) (Catalog# : 18351, Cas# : 1402152-13-9) Copanlisib也称为BAY 80 - 6946,是一个强有力的磷酸肌醇3-激酶(PI3K)抑制剂。Copanlisib抑制PI3K信号通路的激活,起到抑制肿瘤细胞生长和生存的敏感肿瘤细胞群的作用。
• Cenicriviroc (Cenicriviroc) (Catalog# : 179139, Cas# : 497223-25-3) Cenicriviroc(TAK-652, TBR-652) 是一种CCR2和CCR5受体抑制剂，临床上它被用于艾滋病的治疗。
• WWL70 (WWL70) (Catalog# : 16122847, Cas# : 947669-91-2) WWL70 is selective ABHD6 inhibitor, and it has shown anti-inflammatory and neuroprotective effects in animal models of traumatic brain injury and multiple sclerosis.
• VU0467154 (VU0467154) (Catalog# : 18576, Cas# : 1451993-15-9) NEWVU0467154是一种有效的和选择性的M4 PAM.
• KI-696 (KI-696) (Catalog# : 1710132, Cas# : 1799974-70-1) ki-696代表一个优良的低分子量的工具来研究体内Keap1与Nrf2-Nrf2的相互作用。在FBS中发现，在体外实验中显示出良好的效果，并显示出良好的体内效应。
• L-778123 (L-778123) (Catalog# : 1711249, Cas# : 183499-57-2) L-778,123 is an inhibitor of FPTase and GGPTase-I.
• ABT-100 (ABT-100) (Catalog# : 1710131, Cas# : 450839-40-4) abt-100是一种口服的法尼基转移酶抑制剂.
• Pemafibrate (Pemafibrate) (Catalog# : 179221, Cas# : 848259-27-8) NEWPemafibrate, also known as K-877 and (R)-K 13675, is a PPAR alpha agonist. (R)-K-13675 decreases the secretion of inflammatory markers without affecting cell proliferation or tub
• IU1 (IU1) (Catalog# : 51637, Cas# : 314245-33-5) IU1 is a reversible and specific inhibitor of proteasome-associating Usp14. It does not inhibit other deubiquitinating enzymes of the 26S proteasome. It partially inhibits the ub
• Cobicistat(GS-9350) (Cobicistat(GS-9350)) (Catalog# : 51906, Cas# : 1004316-88-4) Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall abs
• CPI-613 (CPI-613) (Catalog# : 51905, Cas# : 95809-78-2) CPI-613 is an E1 pyruvate dehydrogenase (PDH) modulator that prevents cancer cells from metabolizing glucose for energy. CPI-613 has been granted orphan drug status by the US FDA
• CX-4945(Silmitasertib) (CX-4945(Silmitasertib)) (Catalog# : 52024, Cas# : 1009820-21-6) CX-4945 (Silmitasertib) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay).  
• SRT1720 (SRT1720) (Catalog# : 52007, Cas# : 1001645-58-4(HCl);925434-55-5(free base)) SRT1720 is a selectiveSIRT1activator withEC50of 0.16 M, but is >230-fold less potent for SIRT2 and SIRT3. SRT1720(SRT-1720) is an experimental drug that was studied by Sirtris
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