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Apoptosis
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Metabolism
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Aldehydes
Amines
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Anilines
Boronic Acids
Bromides
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Catalysts
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Deuterated
Fluorides
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Indoles and Oxindoles
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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联系我们
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Cas号索引 8
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Cas号索引 8
866598-45-0 | AZD-2207
(Catalog# : 20440)
AZD-2207 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for
851845-37-9 | AZD6703
(Catalog# : 20439)
AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mi
882697-00-9 | Anle138b
(Catalog# : 171553)
Anle138b 是一种口服的、可透过血脑屏障的蛋白质抑制剂。在 α-突
83265-53-6 | 2-氨基-5-三氟甲基苯甲酸
(Catalog# : 20312)
88349-90-0 | A2793
(Catalog# : 20286)
A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TW
868623-40-9 | ABT-384
(Catalog# : 20281)
ABT-384 是 11β-羟基类固醇脱氢酶 1 (HSD-1) 的有效选择性抑制剂,该
872044-70-7 | AN 0128
(Catalog# : 20269)
AN 0128, also known as CRM-0005 and ONT-0001, is a tumour necrosis factor alpha (TNF-
870087-36-8 | Apilimod mesylate ( STA-5326 )
(Catalog# : 23948)
Apilimod, also known as STA-5326, is a potent IL-12/IL-23 inhibitor. Apilimod inhibit
875446-37-0 | Anacetrapib
(Catalog# : 2061701)
Anacetrapib, also known as MK-0859, is a CETP inhibitor being developed to treat hype
898800-26-5 | AZ876
(Catalog# : 19356)
AZ876,又称AZ-876,是一种肝脏X受体激动剂。AZ876可预防病理性心肌
836620-48-5 | AS1842856
(Catalog# : 1811265)
AS1842856是一种细胞可渗透的Foxo1抑制剂,IC50为33 nM,阻断Foxo1的转
880549-30-4 | AMD-070盐酸盐
(Catalog# : 18741)
AMD11070,也称为 AMD070, X4P-001和mavorixafor, 是一种有效的口服生物活
841301-32-4 | 阿莫奈韦
(Catalog# : 186252)
阿莫奈韦是一种 helicase-primase 抑制剂,对 HSVs 具有强效的抗病毒活
851881-60-2 | ADX-47273
(Catalog# : 185173)
ADX-47273是一种强有力的和选择性mGluR5受体PAM(积极的变构调制器),E
80306-38-3 | AR-7
(Catalog# : 179158)
AR-7,亦称非典型维甲酸7,是一种有效的和选择性的自噬(CMA)增
811803-05-1 | 阿帕替尼
(Catalog# : 17022301)
阿帕替尼是一种具有生物口服、选择性的IC50为1 nM的VEGFR2 抑制剂。
878385-84-3 | AZD-5069
(Catalog# : 16122864)
AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neu
848141-11-7 | Alvelestat (AZD9688)
(Catalog# : 16122854)
Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (
88321-09-9 | Aloxistatin (E-64d)
(Catalog# : 16122801)
Aloxistatin (E-64d), is a selective cysteine protease inhibitor or calpain and autoph
859498-05-8 | AGN 205728
(Catalog# : 6111520)
AGN 205728 is a potent and selective RAR antagonist with Ki/IC95 values of 3 nM/ 0.6
893422-47-4 | Akt1 and Akt2-IN-1
(Catalog# : 611804)
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50 = 3.5 nM) and Akt2 (IC50
857531-00-1 (free base); 1431697-86-7 (2HCl) | AT7867
(Catalog# : 161009021)
This ATP-competitive small molecule potently inhibits both AKT and p70S6K activity at
870281-34-8 | Acalisib
(Catalog# : 16071413)
Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of th
865305-30-2 | AF-353
(Catalog# : 16071021)
AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, in
89924-69-6 | ascorbic acid
(Catalog# : 16070919)
(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
844499-71-4 | A-769662
(Catalog# : 16070701)
A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with a
848344-36-5 | AS 602801
(Catalog# : 011913)
AS 602801 is a novel, orally active inhibitor of JNK.
878739-06-1 | AZ 628
(Catalog# : 011120)
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM
882663-88-9 | AMG-47a
(Catalog# : 011107)
AMG-47a is a potent inhibitor of Lck and T cell proliferation.
869357-68-6 | AZD8330
(Catalog# : 010809)
AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 n
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
1497439-74-3 | AD-8007
(Catalog# : 26A018)
AD-8007是一种选择性且可穿透血脑屏障的乙酰辅酶A合成酶2(ACSS2)
1802650-31-2 | ZY-444
(Catalog# : 26A020)
ZY-444是一种通过抑制PC活性发挥抗癌作用的药物。
2306525-79-9 | AD-5584
(Catalog# : 26A019)
AD-5584是一种新型脑渗透性ACSS2抑制剂。
3079716-11-0 | IDB-003
(Catalog# : 26A017)
IDB-003在体内抑制MDA-MB-231肿瘤生长。
1357362-02-7 | Vafidemstat
(Catalog# : 18891)
Vafidemstat又称ORY 2001,是一种赖氨酸特异性组蛋白去甲基化酶(LSD1)
1260247-42-4 | LLL12
(Catalog# : 25075)
LLL12是一种强效的STAT3抑制剂。LLL12在小鼠异种移植物模型中显示出
2758659-09-3 | ECC-5004
(Catalog# : 26A015)
ECC5004是一款每日一次、低剂量、小分子GLP-1受体激动剂。
2911585-37-8 | SILA-123
(Catalog# : 26A014)
SILA-123是一种II型FLT3抑制剂,对FLT3-WT(IC50=2.1 nM)和FLT3-ITD(IC50=1
1214922-52-7 | Encaleret sulfate
(Catalog# : 26A013)
Encaleret是一种正在研究的钙敏感受体的小分子拮抗剂,用于钙稳态
1431303-72-8 | Iadademstat ( ORY-1001 ) hydrochloride
(Catalog# : 26A011)
Iadademstat(ORY-1001)是一种口服活性、高效和选择性的表观遗传酶