Piclidenoson
编号: 16071028
Cas号: 152918-18-8
纯度: 98% by HPLC
Piclidenoson, also known as CF101, is a specific agonist to the A3 adenosine receptor, which inhibits the development of colon carcinoma growth in cell cultures and xenograft murine models. CF101 has been shown to downregulate PKB/Akt and NF-B protein expression level. CF101 potentiates the cytotoxic effect of 5-FU, thus preventing drug resistance. The myeloprotective effect of CF101 suggests its development as an add-on treatment to 5-FU.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Piclidenoson |
|---|---|
| Iupac 化学名称 | (2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide |
| 同义词 | CF101; CF-101 |
| 英文同义词 | CF101; CF-101 |
| 分子式 | C18H19IN6O4 |
| 分子量 | 510.28 |
| Smile | O[C@@H]1[C@H](O[C@H]([C@@H]1O)N1C2=NC=NC(=C2N=C1)NCC1=CC(=CC=C1)I)C(=O)NC |
| InChiKey | HUJXGQILHAUCCV-MOROJQBDSA-N |
| InChi | InChI=1S/C18H19IN6O4/c1-20-17(28)14-12(26)13(27)18(29-14)25-8-24-11-15(22-7-23-16(11)25)21-6-9-3-2-4-10(19)5-9/h2-5,7-8,12-14,18,26-27H,6H2,1H3,(H,20,28)(H,21,22,23)/t12-,13+,14-,18+/m0/s1 |
| Cas号 | 152918-18-8 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
