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抑制剂/受体激动剂
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Anti-infection
Apoptosis
Autophagy
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DNA Damage
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MAPK
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Cas号索引 1
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Cas号索引 1
1497439-74-3 | AD-8007
(Catalog# : 26A018)
AD-8007是一种选择性且可穿透血脑屏障的乙酰辅酶A合成酶2(ACSS2)
16431-36-0 | 5-氮杂螺[4.5]癸-5-溴化鎓
(Catalog# : 26B001)
1129403-56-0 | Amcasertib (同义词: BBI503)
(Catalog# : 25172)
1037837-27-6 | ARN14494
(Catalog# : 25156)
ARN14494 是一种选择性丝氨酸棕榈酰转移酶 (SPT) 抑制剂,它是鞘脂
1581714-49-9 | Atuzabrutinib
(Catalog# : 25145)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
137945-48-3 | Ajulemic acid
(Catalog# : 25112)
1047644-62-1 | Afuresertib
(Catalog# : 25111)
Afuresertib, also known as GSK-2110183 or GSK-2110183C, is an orally bioavailable inh
122510-61-6 | AF-615
(Catalog# : 24135)
AF-615 is a novel Inhibitor of CDT1/Geminin Protein Complex, promoting DNA Damage and
1361563-03-2 | Aldoxorubicin hydrochloride
(Catalog# : 24051)
Aldoxorubicin (INNO-206) hydrochloride is an albumin-binding proagent of Doxorubicin
1174130-61-0 | Aticaprant
(Catalog# : 24036)
Aticaprant (CERC-501) is a potent and centrally-penetrantkappa opioidreceptor antagon
1945941-09-2 | ADT-007
(Catalog# : 20664)
ADT-007 is a potent and orally active pan-RAS inhibitor with strong anticancer effect
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) 是一种抗纤维化剂,降低胶原蛋白 I 和 III 的 mRNA
1802148-05-5 | AZD7986
(Catalog# : 20648)
Brensocatib, also known as AZD7986, INS 1007, is an oral reversible inhibitor of dipe
1332881-26-1(free base) | ABI-231
(Catalog# : 20574)
ABI-231 is a potent, orally bioavailable tubulin inhibitor that interacts with the co
173937-91-2 | Atrasentan
(Catalog# : 20540)
Atrasentan, also known as ABT-627, is a orally available ETA receptor antagonist with
19947-39-8 | 3-氨基-3-(4-氯苯基)丙酸
(Catalog# : 20515)
1035688-66-4 | ASLAN003
(Catalog# : 20507)
ASLAN003 is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehy
112892-51-0 | Alentemol HBr
(Catalog# : 20502)
Alentemol, also known as U-66444B and alentamol, is a selective dopamine autoreceptor
1034190-08-3 | ALZ-801
(Catalog# : 20450)
ALZ-801 is an oral, small-molecule inhibitor of beta amyloid (Aβ) oligomer formation
1398496-82-6 | Afizagabar
(Catalog# : 20429)
Afizagabar, also known as S44819 and Egis 13529, is a GABA receptor antagonist.
1060801-23-1 | 1-(6-氨基吡啶-2-基)乙-1-酮
(Catalog# : 171453)
1-(6-氨基吡啶-2-基)乙-1-酮, CAS 1060801-23-1.
1215932-56-1 | 2-吗啉基-3-溴-5-氨基吡啶
(Catalog# : 20425)
1770840-43-1 | 7-碘吡咯并[2,1-F][1,2,4]三嗪-4-胺
(Catalog# : 20397)
1518800-35-5 | Afabicin
(Catalog# : 20303)
Afabicin (formerly Debio 1450, AFN-1720) is a prodrug of afabicin desphosphono, an en
1446711-81-4 | Acoramidis (AG-10 )
(Catalog# : 20300)
Acoramidis (formerly AG10) is an investigational, orally-administered small molecule
1003566-93-5 | AZD-4818
(Catalog# : 20297)
AZD-4818 is a chemokine CCR1 antagonist that is used for the treatment of chronic obs
1467093-03-3 (free base) | Adavivint
(Catalog# : 20289)
1899921-05-1 | Almonertinib
(Catalog# : 20267)
Almonertinib is an orally available inhibitor of the epidermal growth factor receptor
1095565-81-3 | AMG-221
(Catalog# : 21223)
AMG-221, BVT-83370, is a potent and selective 11β-HSD1 inhibitor. AMG-221 decreased
1258417-54-7 | ACT-389949 (ACT389949)
(Catalog# : 20211801)
ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive-Oxygen-Species-ROS
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
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--
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--
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--
On Sale
新产品
天然化合物
最新产品
845959-55-9 | Mitoquinol mesylate (MitoQ)
(Catalog# : 26A042)
Mitoquinol mesylate (MitoQ) 是一种线粒体靶向抗氧化剂,具体而言,它
1246960-09-7 | SPG-601 ( VSN-16R )
(Catalog# : 24042)
SPG-601(原名VSN-16R)是一种口服给药、同类首创的小分子药物,是
1421438-81-4 | LY3039478 ( Crenigacestat )
(Catalog# : 17021601)
LY3039478 ( Crenigacestat ) 是一种选择性 NOTCH1 抑制剂,通过阻断 VEGFA/
72882-78-1 | PF-9366
(Catalog# : 184107)
PF-9366是一种新型的人蛋氨酸腺苷转移酶2A (Mat2A),肝外同种型。
2925330-18-1 | MAT2A-IN-22
(Catalog# : 26A021)
MAT2A-IN-22 (Compound 29-1) 是一种可透过血脑屏障的和口服有效的 MAT2A
| Pantothenate kinase-IN-3
(Catalog# : 26A041)
泛酸激酶-IN-3(亦称化合物21,https://doi.org/10.1021/acs.jmedchem.5c03452)
2361124-03-8 | Claziprotamidum ( Claziprotamide ; BBP-671 )
(Catalog# : 26A040)
Claziprotamidum(Claziprotamide;BBP-671)是一种强效、口服有效且能透过
2170608-85-0 | PZ-3022
(Catalog# : 26A039)
PZ-3022是一种别构型的PanK激活剂,能够抵消C3-CoA的抑制作用。
2170608-82-7 | PZ-2891
(Catalog# : 193282)
PZ-2891是一种强效的、选择性的、口服活性泛酸激酶(PANK)调制剂,
902614-04-4 | Pantothenate kinase-IN-2
(Catalog# : 26A038)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,