武汉永璨生物科技有限公司
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抑制剂/受体激动剂
Angiogenesis
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Apoptosis
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JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
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PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
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分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
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Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
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订购信息
联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 P
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产品名字索引 P
PF-04217903
(Catalog# : 010807, Cas# :
956905-27-4
)
PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susce
PF-5274857
(Catalog# : 010423, Cas# :
1373615-35-0
)
PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (
Pravadoline
(Catalog# : 010415, Cas# :
92623-83-1
)
Coming soon!
PD318088
(Catalog# : 010414, Cas# :
391210-00-7
)
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binds simultaneously w
PF-04691502
(Catalog# : 123020, Cas# :
1013101-36-4
)
PF-04691502 is an ATP-competitive PI3K(///)/mTOR dual inhibitor with Ki of 1.8 nM/2.1
PKC412
(Catalog# : 123013, Cas# :
120685-11-2
)
PKC412 is a broad spectrum protein kinase inhibitor; inhibits conventional PKC isofor
Plerixafor octahydrochloride
(Catalog# : 123004, Cas# :
155148-31-5
)
Plerixafor octahydrochloride is a chemokine receptor antagonist for CXCR4 and CXCL12-
PF-3084014
(Catalog# : 122950, Cas# :
1290543-63-3
)
PF-3084014 is a novel -secretase inhibitor that reduces amyloid-beta (Abeta) producti
Pacritinib(SB1518)
(Catalog# : 122941, Cas# :
937272-79-2
)
Pacritinib (SB1518) 是一种高选择性激酶抑制剂,对 JAK2、FLT3、IRAK1 和
PHA-848125
(Catalog# : 122916, Cas# :
802539-81-7
)
PHA-848125 is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM; &g
PI-3065
(Catalog# : 122908, Cas# :
955977-50-1
)
PI-3065 is a novel potent and selective PI3K p110 inhibitor with IC50 of 15 nM; exhib
PD 123319
(Catalog# : 122903, Cas# :
130663-39-7
)
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of
PNU-282987
(Catalog# : 122827, Cas# :
123464-89-1
)
PNU-282987 is a selective 7 nicotinic acetylcholine receptor(7 nAChR) agonist with Ki
PF-431396
(Catalog# : 122818, Cas# :
717906-29-1
)
PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK
Posaconazole
(Catalog# : 122815, Cas# :
171228-49-2
)
Posaconazole is a broad-spectrum, second generation, triazole compound with antifunga
PQ401
(Catalog# : 122806, Cas# :
196868-63-0
)
PQ401, a selective insulin-like growth factor-1 receptor blocker, is a novel diarylur
Pardoprunox
(Catalog# : 122523, Cas# :
269718-84-5
)
Pardoprunox is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT
PKC-IN-1
(Catalog# : 122520, Cas# :
1046787-18-1
)
PKC-IN-1 is a poent PKC beta II inhibitor with Ki of 14.9 nM; compound example H6 fro
PF-04447943
(Catalog# : 122515, Cas# :
1082744-20-4
)
PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and
PD-0325901
(Catalog# : 122405, Cas# :
391210-10-9
)
PD-0325901 i a potent bioavailable and selective MEK inhibitor, which targets mitogen
P005672 hydrochloride
(Catalog# : 122302, Cas# :
1035979-44-2
)
P005672 hydrochloride is used for antibacterial/anti-inflammatory acne treatment.
Pirodavir
(Catalog# : 122216, Cas# :
124436-59-5
)
Pirodavir is the prototype of a novel class of broad-spectrum antipicornavirus compou
PD173074
(Catalog# : 122212, Cas# :
219580-11-7
)
PD173074 is a small-molecule FGFR3-selective tyrosine kinase inhibitor (TKI), as a th
Pyroxamide
(Catalog# : 121802, Cas# :
382180-17-8
)
Pyroxamide is a synthetic derivative of hydroxamic acid with antineoplastic propertie
PKI-402
(Catalog# : 121421, Cas# :
1173204-81-3
)
PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3K/// and mTOR with IC50
PHA-665752
(Catalog# : 121418, Cas# :
477575-56-7
)
PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9
Pemetrexed disodium
(Catalog# : 120704, Cas# :
150399-23-8
)
Coming soon!
PX-478
(Catalog# : 111307, Cas# :
685847-78-3
)
PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potentia
Pardoprunox hydrochloride
(Catalog# : 111010, Cas# :
269718-83-4
)
Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and
PD153035 Hcl
(Catalog# : 111003, Cas# :
183322-45-4
)
PD153035 Hcl is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM an
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive-Oxygen-Species-ROS
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Mitoquinol mesylate (MitoQ)
(Catalog# : 26A042, Cas# :
845959-55-9
)
Mitoquinol mesylate (MitoQ) 是一种线粒体靶向抗氧化剂,具体而言,它
SPG-601 ( VSN-16R )
(Catalog# : 24042, Cas# :
1246960-09-7
)
SPG-601(原名VSN-16R)是一种口服给药、同类首创的小分子药物,是
LY3039478 ( Crenigacestat )
(Catalog# : 17021601, Cas# :
1421438-81-4
)
LY3039478 ( Crenigacestat ) 是一种选择性 NOTCH1 抑制剂,通过阻断 VEGFA/
PF-9366
(Catalog# : 184107, Cas# :
72882-78-1
)
PF-9366是一种新型的人蛋氨酸腺苷转移酶2A (Mat2A),肝外同种型。
MAT2A-IN-22
(Catalog# : 26A021, Cas# :
2925330-18-1
)
MAT2A-IN-22 (Compound 29-1) 是一种可透过血脑屏障的和口服有效的 MAT2A
Pantothenate kinase-IN-3
(Catalog# : 26A041)
泛酸激酶-IN-3(亦称化合物21,https://doi.org/10.1021/acs.jmedchem.5c03452)
Claziprotamidum ( Claziprotamide ; BBP-671 )
(Catalog# : 26A040, Cas# :
2361124-03-8
)
Claziprotamidum(Claziprotamide;BBP-671)是一种强效、口服有效且能透过
PZ-3022
(Catalog# : 26A039, Cas# :
2170608-85-0
)
PZ-3022是一种别构型的PanK激活剂,能够抵消C3-CoA的抑制作用。
PZ-2891
(Catalog# : 193282, Cas# :
2170608-82-7
)
PZ-2891是一种强效的、选择性的、口服活性泛酸激酶(PANK)调制剂,
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,