PNU-159682
编号: 16071409
Cas号: 202350-68-3
纯度: 98% by HPLC
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin). PNU-159682 interacts with DNA fragments d(CGTACG)(2), d(CGATCG)(2) and d(CGCGCG)(2) and shows a strong but reversible binding to G:C base pairs.
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化学信息
| 名称 | PNU-159682 |
|---|---|
| Iupac 化学名称 | (7S,9S)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7-(((1S,3R,4aS,9S,9aR,10aS)-9-methoxy-1-methyloctahydro-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl)oxy)-7,9,10,12-tetrahydrotetracen-5(8H)-one |
| 同义词 | PNU-159682; PNU 159682; |
| 英文同义词 | PNU-159682; PNU 159682; |
| 分子式 | C32H37NO12 |
| 分子量 | 627.643 |
| Smile | OC1=C2C(C=3C(=CC=CC3CC2=C(C=2C[C@](C[C@@H](C12)O[C@H]1C[C@H]2[C@H](O[C@@H]3[C@H](OCCN32)OC)[C@@H](O1)C)(C(CO)=O)O)O)OC)=O |
| InChiKey | NOGFHSKHNYEVCK-DQTAREDWSA-N |
| InChi | InChI=1S/C32H37NO12/c1-14-29-18(33-7-8-42-31(41-3)30(33)45-29)10-22(43-14)44-20-12-32(39,21(35)13-34)11-17-24(20)28(38)25-16(26(17)36)9-15-5-4-6-19(40-2)23(15)27(25)37/h4-6,14,18,20,22,29-31,34,36,38-39H,7-13H2,1-3H3/t14-,18-,20-,22-,29+,30+,31-,32-/m0/s1 |
| Cas号 | 202350-68-3 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
