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PF-04880594

Catalog No.: 012008
Cas No.: 1111636-35-1
Purity : 98% 
012008 - PF-04880594 | CAS 1111636-35-1

Catalog number : 012008

CAS number : 1111636-35-1

分子式 : C19H16F2N8 

分子量 : 394.38 

Iupac 化学名称 : 3-((4-(1-(2,2-difluoroethyl)-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propanenitrile 

Smile : FC(CN1N=C(C(=C1)C1=NC(=NC=C1)NCCC#N)C=1C=C2C(=NC1)NC=C2)F

InChiKey : HFYMVDKBZONUOJ-UHFFFAOYSA-N

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同义词PF04880594; PF 04880594 
英文同义词PF04880594; PF 04880594 
分子式C19H16F2N8 
分子量394.38 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileFC(CN1N=C(C(=C1)C1=NC(=NC=C1)NCCC#N)C=1C=C2C(=NC1)NC=C2)F
InChiKeyHFYMVDKBZONUOJ-UHFFFAOYSA-N
InChiInChI=1S/C19H16F2N8/c20-16(21)11-29-10-14(15-3-7-25-19(27-15)24-5-1-4-22)17(28-29)13-8-12-2-6-23-18(12)26-9-13/h2-3,6-10,16H,1,5,11H2,(H,23,26)(H,24,25,27)
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PF-04880594 is a RAF inhibitor, which induces ERK phosphorylation and RAF dimerization in those epithelial tissues that undergo hyperplasia. 

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