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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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技术服务
定制合成
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订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 M
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产品名字索引 M
mTOR-IN-1
(Catalog# : 611820, Cas# :
1207358-59-5
)
mTOR-IN-1 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 1.5
Miltefosine
(Catalog# : 161009023, Cas# :
58066-85-6
)
Miltefosine targets cellular membranes, modulating cell membrane permeability, membra
1-METHYL-5-NITRO-1H-INDOLE
(Catalog# : 169701, Cas# :
29906-67-0
)
1-METHYL-5-NITRO-1H-INDOLE CAS#29906-67-0
Mubritinib
(Catalog# : 16071022, Cas# :
366017-09-6
)
Mubritinib, also known as TAK-165, is a protein kinase inhibitor which was under deve
MK-8245
(Catalog# : 16070814, Cas# :
1030612-87-3
)
MK-8245
MLN120B
(Catalog# : 16070813, Cas# :
783348-36-7
)
MLN120B
MS417
(Catalog# : 16070106, Cas# :
916489-36-6
)
MS417, also known as GTPL7512, is a potent and selective BRD4 inhibitor. MS417 inhibi
Molidustat (BAY85-3934)
(Catalog# : 16062901, Cas# :
1154025-82-6
)
Molidustat (BAY85-3934)
MK-8931 ( Verubecestat )
(Catalog# : 1662118, Cas# :
1286770-55-5
)
MK-8931(verubecestat)是一种BACE抑制剂,是由默沙东公司研制开发。主
Methyl 2,5-dimethylnicotinate
(Catalog# : 16062101, Cas# :
63820-72-4
)
Methyl 2,5-dimethylnicotinate
MDK-5220
(Catalog# : 16060603, Cas# :
1796565-52-0
)
MDK-5220 exhibits an orexin agonist activity and is expected to be useful as an excel
MK-5172
(Catalog# : 032514, Cas# :
1350514-68-9
)
Coming soon!
Mirodenafil
(Catalog# : 030904, Cas# :
862189-95-5
)
Coming soon!
MK-2866
(Catalog# : 030901, Cas# :
1202044-20-9
)
Coming soon!
MCC950
(Catalog# : 030101, Cas# :
210826-40-7
)
MCC950 is a potent, selective, small-molecule inhibitor of NLRP3 with IC50 of 7.5 nM
MRE-269
(Catalog# : 020106, Cas# :
475085-57-5
)
MRE-269 is a long-acting and highly selective prostacyclin receptor agonist.
MSX-122
(Catalog# : 011906, Cas# :
897657-95-3
)
MSX-122 is a n orally bioavailable inhibitor of CXCR4 with potential antineoplastic a
ME-143
(Catalog# : 011902, Cas# :
852536-39-1
)
ME -143 is a derivative of triphendiol and is a highly potent, pan acting ant-cancer.
MK-2206
(Catalog# : 011805, Cas# :
1032349-93-1
)
MK-2206 2Hcl is an orally bioavailable allosteric inhibitor of the serine/threonine p
MK-8033
(Catalog# : 011801, Cas# :
1001917-37-8
)
MK8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt
ML324
(Catalog# : 011301, Cas# :
1222800-79-4
)
ML324 is a potent JMJD2 demethylase inhibitor with demonstrated antiviral activity.
MK-1775
(Catalog# : 011110, Cas# :
955365-80-7
)
MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM; hinders G2 DNA
MK-2461
(Catalog# : 010806, Cas# :
917879-39-1
)
MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met.
Medetomidine hydrochloride
(Catalog# : 010606, Cas# :
86347-15-1
)
Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is use
MK-2048
(Catalog# : 010424, Cas# :
870005-19-9
)
MK-2048 is a second generation integrase inhibitor, intended to be used against HIV i
MK7622
(Catalog# : 51627, Cas# :
1227923-29-6
)
MK-7622isused as adjunctive therapy to acetylcholinesterase inhibitors (AChEIs) for t
MK-4827
(Catalog# : 123007, Cas# :
1038915-60-4
)
MK-4827 is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with grea
MK-0752
(Catalog# : 122949, Cas# :
471905-41-6
)
MK-0752 is a moderately potent -secretase inhibitor, which reduces A40 production wit
MK8745
(Catalog# : 122819, Cas# :
885325-71-3
)
MK-8745 is a novel Aurora-A specific inhibitor. MK8745 induced apoptotic cell death i
MK 886
(Catalog# : 122217, Cas# :
118414-82-7
)
MK 886 is a leukotriene antagonist. It may perform this by blocking the 5-lipoxygenas
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil 是一种有效的、高选择性的口服活性抑制剂,针对 Rho 相关
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib 是一种口服、有效、选择性的小分子抑制剂,针对 menin 和
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib是一种在研口服丝裂原活化蛋白激酶活化蛋白激酶2(MK2
Zongertinib ( BI 1810631 )
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] 是一种人表皮生长因子受体 2 (HER2) 抑制剂。
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib是一种作用于非受体酪氨酸蛋白激酶 (TYK2)靶点的抑制
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 为BRD4降解剂,其在小鼠荷瘤异种移植模型中展现出显著抑
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) 是一种抗纤维化剂,降低胶原蛋白 I 和 III 的 mRNA
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).