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Catalog No.: 6111524
Cas No.: 219832-49-2
Purity : 98% 
6111524 - MP-A08 | CAS 219832-49-2

Catalog number : 6111524

CAS number : 219832-49-2

分子式 : C27H25N3O4S2 

分子量 : 519.64 

Iupac 化学名称 : MP-A08 

InChiKey :

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同义词MP A08 
英文同义词MP A08 
外观crystalline solid 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
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MP-A08 is a highly selective ATP competitive SK inhibitor that targets both SK1 and SK2 with Kivalues of 6.9 0.8 M and 27 3 M, respectively.

MP-A08 blocks pro-proliferative signalling pathways, induces mitochondrial-associated apoptosis in a SK-dependent manner, and reduces the growth of human lung adenocarcinoma tumours in a mouse xenograft model by both inducing tumour cell apoptosis and inhibiting tumour angiogenesis. MP-A08 inhibit SK-2, cause a decrease in EC barrier integrity in vitro in both cell type.

MP-A08 suppresses the growth of human lung tumor xenografts in mice.


219832-49-2 - Request Bulk Quote

219832-49-2 - Request Bulk Quote