MP-A08
编号: 6111524
Cas号: 219832-49-2
纯度: 98%
MP-A08 is a highly selective ATP competitive SK inhibitor that targets both SK1 and SK2 with Kivalues of 6.9 0.8 M and 27 3 M, respectively.
MP-A08 blocks pro-proliferative signalling pathways, induces mitochondrial-associated apoptosis in a SK-dependent manner, and reduces the growth of human lung adenocarcinoma tumours in a mouse xenograft model by both inducing tumour cell apoptosis and inhibiting tumour angiogenesis. MP-A08 inhibit SK-2, cause a decrease in EC barrier integrity in vitro in both cell type.
MP-A08 suppresses the growth of human lung tumor xenografts in mice.
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化学信息
| 名称 | MP-A08 |
|---|---|
| Iupac 化学名称 | MP-A08 |
| 同义词 | MP A08 |
| 英文同义词 | MP A08 |
| 分子式 | C27H25N3O4S2 |
| 分子量 | 519.64 |
| InChiKey | |
| InChi | |
| Cas号 | 219832-49-2 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
