M2I-1, also known as Mad2 Inhibitor-1, is Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. M2I-1 disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. Cellular studies revealed that M2I-1 weakens the SAC response, indicating that the compound might be active in cells.
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化学信息
| 名称 | M2I-1 |
| Iupac 化学名称 | M2I-1 |
| 同义词 | M2I1; M2I 1. Mad2 Inhibitor-1 |
| 英文同义词 | M2I1; M2I 1. Mad2 Inhibitor-1 |
| 分子式 | C19H24N4O4S |
| 分子量 | 404.485 |
| InChiKey | |
| InChi | |
| Cas号 | 312271-03-7 |
| 相关CAS号 | |
| 外观性状 | crystalline solid |
| 纯度 | 98% |
| 存储 | 3 years -20ºCpowder |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |