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ML390

Catalog No.: 16122749
Cas No.:
Purity : 98% 
16122749 - ML390

Catalog number : 16122749

CAS number :

分子式 : C21H21F3N2O3 

分子量 : 406.4 

Iupac 化学名称 : ML390 

Smile : C[Si](C)(C)CSCCl

InChiKey : IKWIERSJEROYFH-UHFFFAOYSA-N

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同义词N/A 
英文同义词N/A 
分子式C21H21F3N2O3 
分子量406.4 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
SmileC[Si](C)(C)CSCCl
InChiKeyIKWIERSJEROYFH-UHFFFAOYSA-N
InChiInChI=1S/C5H13ClSSi/c1-8(2,3)5-7-4-6/h4-5H2,1-3H3
MDLMFCD17013410
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ML390 is a human DHODH inhibitor that induces differentiation in acute myeloid leukemia.ML390 was active with an ED50 (effective concentration triggering 50% of its maximal differentiation activity) of 2 M in murine and human AML cell lines, offering insight into the mechanism of overcoming differentiation arrest. DHODH inhibitors demonstrated effective at prolonging survival in animal models of leukemia 

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