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ML390

编号: 16122749
Cas号:
纯度: 98% 

ML390 is a human DHODH inhibitor that induces differentiation in acute myeloid leukemia.ML390 was active with an ED50 (effective concentration triggering 50% of its maximal differentiation activity) of 2 M in murine and human AML cell lines, offering insight into the mechanism of overcoming differentiation arrest. DHODH inhibitors demonstrated effective at prolonging survival in animal models of leukemia 

仅供研究使用。 我们不向患者出售。

化学信息

名称ML390
Iupac 化学名称ML390 
同义词N/A 
英文同义词N/A 
分子式C21H21F3N2O3 
分子量406.4 
SmileC[Si](C)(C)CSCCl
InChiKeyIKWIERSJEROYFH-UHFFFAOYSA-N
InChiInChI=1S/C5H13ClSSi/c1-8(2,3)5-7-4-6/h4-5H2,1-3H3
Cas号
MDLMFCD17013410
相关CAS号

订购信息

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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16122749 - ML390

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