GDC-0134
编号: 20432
Cas号: 1637394-01-4
纯度: ≧98.0%
GDC-0134是一种MAP3K12（DLK）抑制剂。
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | GDC-0134 |
|---|---|
| Iupac 化学名称 | 3-(Difluoromethoxy)-5-[2-(3,3-difluoropyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyridin-2-amine |
| 同义词 | GDC-0134; GDC0134; GDC 0134; RG-6000; RG 6000; RG6000 |
| 英文同义词 | GDC-0134; GDC0134; GDC 0134; RG-6000; RG 6000; RG6000 |
| 分子式 | C19H20F4N6O2 |
| 分子量 | 440.39 |
| Smile | NC1=NC=C(C2=NC(N5CC(F)(F)CC5)=NC(N3[C@]4([H])CO[C@](C4)([H])C3)=C2)C=C1OC(F)F |
| InChiKey | SKMKJBYBPYBDMN-RYUDHWBXSA-N |
| InChi | InChI=1S/C19H20F4N6O2/c20-17(21)31-14-3-10(6-25-16(14)24)13-5-15(29-7-12-4-11(29)8-30-12)27-18(26-13)28-2-1-19(22,23)9-28/h3,5-6,11-12,17H,1-2,4,7-9H2,(H2,24,25)/t11-,12-/m0/s1 |
| Cas号 | 1637394-01-4 |
| 相关CAS号 | 1637394-01-4 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | 固体粉末 |
|---|---|
| 纯度 | ≧98.0% |
| 存储 | 短期（几天到几周）为0-4摄氏度，长期（几个月）为-20摄氏度 |
| 可溶性 | 溶于DMSO |
| 处理方式 | Refer to MSDS |
| 运输条件 | 作为非危险化学品在环境温度下装运。这种产品在正常运输和海关工作期间可以稳定几周. |
| 海关编码 | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | GDC-0134 is a MAP3K12 (DLK) Inhibitor which had been in early clinical trials at Genentech for the treatment of amyotrophic lateral sclerosis. However, the company discontinued the development of the product. |
Not available
