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MK-4101

编号: 6111008
Cas号: 935273-79-3
纯度: 98% 

MK-4101 is a potent SMO Inhibitor of the Hedgehog Pathway

MK-4101 is a potent SMO Inhibitor of the Hedgehog Pathway, highly active against Medulloblastoma and Basal Cell Carcinoma. target:SMO In vivo: MK-4101 was highly efficacious against primary medulloblastoma and BCC developing in the cerebellum and skin of Ptch1+/- mice. In vitro: MK-4101 induce deregulation of cell cycle and block of DNA replication in tumors. MK-4101 targets the Hh pathway in tumor cells, showing the maximum inhibitory effect on Gli1. MK-4101 also induce deregulation of cell cycle and block of DNA replication in tumors.

 

仅供研究使用。 我们不向患者出售。

化学信息

名称MK-4101
Iupac 化学名称MK-4101 
同义词MK 4101, MK4101 
英文同义词MK 4101, MK4101 
分子式C24H24F5N5O 
分子量493.47 
InChiKey
InChi
Cas号935273-79-3
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

6111008 - MK-4101 | CAS 935273-79-3

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