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Miltefosine

Catalog No.: 161009023
Cas No.: 58066-85-6
Purity : 98% by HPLC 
161009023 - Miltefosine | CAS 58066-85-6

Catalog number : 161009023

CAS number : 58066-85-6

分子式 : C21H46NO4P 

分子量 : 407.57 

Iupac 化学名称 : hexadecyl (2-(trimethylammonio)ethyl) phosphate 

Smile : P(=O)(OCCCCCCCCCCCCCCCC)(OCC[N+](C)(C)C)[O-]

InChiKey : PQLXHQMOHUQAKB-UHFFFAOYSA-N

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同义词iltefosin CHePCHexadecylphosphocholineHDPCHexadecylphosphorylcholineMiltefosinum; mpavido; Miltex; Choline Phosphate Hexadecyl Ester Hydroxide Inner Salt; hexadecylphosphocholine; Miltefosin; Miltefosina; Miltefosinum; Foreign brand name: Miltex ; Abbreviation: HDPC Code name: D18506; 
英文同义词iltefosin CHePCHexadecylphosphocholineHDPCHexadecylphosphorylcholineMiltefosinum; mpavido; Miltex; Choline Phosphate Hexadecyl Ester Hydroxide Inner Salt; hexadecylphosphocholine; Miltefosin; Miltefosina; Miltefosinum; Foreign brand name: Miltex ; Abbreviation: HDPC Code name: D18506; 
分子式C21H46NO4P 
分子量407.57 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileP(=O)(OCCCCCCCCCCCCCCCC)(OCC[N+](C)(C)C)[O-]
InChiKeyPQLXHQMOHUQAKB-UHFFFAOYSA-N
InChiInChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3
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Miltefosine targets cellular membranes, modulating cell membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. As an immunomodulator, miltefosine stimulates T-cells, macrophages and the expression of interleukin 3 (IL-3), granulocyte-macrophage colony stimulating factor (GM-CSF), and interferon gamma (INF-gamma). Check for active clinical trials or closed clinical trials using this agent. 

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