ML346
Catalog No.: 611940
Cas No.: 100872-83-1
Purity : 98%
Catalog number : 611940
CAS number : 100872-83-1
分子式 : C14H12N2O4
分子量 : 272.26
Iupac 化学名称 : ML346
InChiKey :
| Packaging | Price | Availability | Purity | Estimated Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry |
| 同义词 | ML-346 |
|---|---|
| 英文同义词 | ML-346 |
| 分子式 | C14H12N2O4 |
| 分子量 | 272.26 |
| 外观 | crystalline solid |
| 纯度 | 98% |
| 可溶性 | Soluble in DMSO |
| 存储 | 3 years -20ºCpowder |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
| InChiKey | |
| InChi |
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ML346 is a novel activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.
ML346 has good chemical stability, significantly high water solubility, is not reactive with excess glutathione, and is cell permeable. The probe ML346 will help elucidate roles for activation of Hsp70 and HSF-1 in the prevention and progression of cancers, cellular aging, and metabolic and neurodegenerative disorders. ML346 is a novel modulator of proteostasis for protein conformational diseases.
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