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ML346

Catalog No.: 611940
Cas No.: 100872-83-1
Purity : 98% 
611940 - ML346 | CAS 100872-83-1

Catalog number : 611940

CAS number : 100872-83-1

分子式 : C14H12N2O4 

分子量 : 272.26 

Iupac 化学名称 : ML346 

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同义词ML-346 
英文同义词ML-346 
分子式C14H12N2O4 
分子量272.26 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
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ML346 is a novel activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay.

ML346 has good chemical stability, significantly high water solubility, is not reactive with excess glutathione, and is cell permeable. The probe ML346 will help elucidate roles for activation of Hsp70 and HSF-1 in the prevention and progression of cancers, cellular aging, and metabolic and neurodegenerative disorders. ML346 is a novel modulator of proteostasis for protein conformational diseases.


 

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