武汉永璨生物科技有限公司
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抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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PROTAC
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分子砌块
Aldehydes
Amines
Amino Acids
Anilines
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Bromides
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Deuterated
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订购信息
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
Nuclear Receptor
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 A
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产品名字索引 A
A-674563 hydrochloride
(Catalog# : 611802, Cas# :
2070009-66-2
)
A-674563 hydrochloride is a potent selective Akt1 inhibitor with an IC50 of 14 nM; al
Avasimibe
(Catalog# : 161014003, Cas# :
166518-60-1
)
Avasimibe is a selective inhibitor of Cholesterol Acyltransferase 1 and CYP2C9. Avasi
Apoptozole
(Catalog# : 161014002, Cas# :
1054543-47-3
)
Apoptosis Activator VII, Apoptozole is a cell-permeable imidazole compound that direc
AT7867
(Catalog# : 161009021, Cas# :
857531-00-1 (free base); 1431697-86-7 (2HCl)
)
This ATP-competitive small molecule potently inhibits both AKT and p70S6K activity at
AKT inhibitor VIII
(Catalog# : 161009020, Cas# :
612847-09-3
)
AKT inhibitor VIII suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric c
AS-604850
(Catalog# : 160926014, Cas# :
648449-76-7
)
Treatment with this PI3K inhibitor enhanced myelination and axon number in the spinal
AS-252424
(Catalog# : 160926012, Cas# :
900515-16-4
)
AS-252424 is a potent and selective small-molecule PI3Kgamma inhibitor. Oral administ
AS-605240
(Catalog# : 160926007, Cas# :
648450-29-7
)
Orally administration of AS605240 significantly prevented lung inflammation and reduc
Acalisib
(Catalog# : 16071413, Cas# :
870281-34-8
)
Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of th
AZD8330
(Catalog# : 16071301, Cas# :
1204531-17-8
)
AZD8330
AZD-4547
(Catalog# : 16071109, Cas# :
1394854-62-6
)
AZD-4547
Apaziquone
(Catalog# : 16071104, Cas# :
114560-48-4
)
Apaziquone, also known as EO9, EOquin, is a n indolequinone bioreductive prodrug and
AF-353
(Catalog# : 16071021, Cas# :
865305-30-2
)
AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, in
AMG-517
(Catalog# : 16071001, Cas# :
659730-32-2
)
AMG 517 is a potent and selective TRPV1 antagonist, and antagonizes capsaicin, proton
ascorbic acid
(Catalog# : 16070919, Cas# :
89924-69-6
)
(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
ARS-853
(Catalog# : 16070910, Cas# :
1629268-00-3
)
ARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS dri
Asunaprevir
(Catalog# : 16070810, Cas# :
630420-16-5
)
Asunaprevir, also known as BMS-650032, is an inhibitor of the hepatitis C virus enzym
AZD2281(Olaparib)
(Catalog# : 92801, Cas# :
763113-22-0
)
Olaparib (AZD-2281, trade name Lynparza) is an FDA-approved targeted therapy for canc
AZ91498
(Catalog# : 16070801, Cas# :
773871-93-5
)
AZ91498
A-769662
(Catalog# : 16070701, Cas# :
844499-71-4
)
A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with a
AM-580
(Catalog# : 16062701, Cas# :
102121-60-8
)
AM-580 is a potent RARalpha agonist. AM580 has powerful and selective cyto-differenti
Aurora A Inhibitor I
(Catalog# : 16062401, Cas# :
1158838-45-9
)
Aurora A Inhibitor I
AN-2718
(Catalog# : 16062104, Cas# :
174672-06-1
)
AN-2718
AZ7371
(Catalog# : 16062102, Cas# :
1494675-86-3
)
AZ7371 is a a novel non-covalent DprE1 inhibitor
Amcinafide
(Catalog# : 16062001, Cas# :
7332-27-6
)
Amcinafide
AZD-3965
(Catalog# : 33001, Cas# :
1448671-31-5
)
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a bindi
AVN944
(Catalog# : 022201, Cas# :
297730-17-7
)
AVN944 is an orally available, synthetic small molecule with potential antineoplastic
Arry-380
(Catalog# : 021801, Cas# :
937265-83-3
)
ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent again
A-1331852
(Catalog# : 012603, Cas# :
1430844-80-6
)
Coming soon!
A-1155463
(Catalog# : 012602, Cas# :
1235034-55-5
)
A-1155463 is a highly potent and selective BCL-XL inhibitor.
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Kartogenin ( KGN )
(Catalog# : 52215, Cas# :
4727-31-5
)
Kartogenin(KGN)是一种合成小分子,通过激活smad-4/5通路刺激软骨细
Imisopasem manganese ( M40403; GC4403 )
(Catalog# : 72602, Cas# :
218791-21-0
)
Imisopasem manganese ( M40403; GC4403 ) 是一种稳定的非肽类 MnSOD 类似物,
Apecotrep (BI 764198)
(Catalog# : 26A048, Cas# :
2311863-36-0
)
Apecotrep(BI 764198)是一种潜在的同类首创、口服、选择性的TRPC6抑
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制
Gridegalutamide
(Catalog# : 26A044, Cas# :
2446929-86-6
)
格列德加鲁胺是一种具有口服生物利用度的雄激素受体(AR)降解
BMS-986365 (别名: CC-94676 )
(Catalog# : 25138, Cas# :
2446928-30-7
)
BMS-986365,也称为 CC-94676,是一种口服生物可利用的雄激素受体 (A
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
VAS3947
(Catalog# : 20302, Cas# :
869853-70-3
)
VAS3947是一种低微摩尔浓度的NADPH氧化酶活性的选择性抑制剂,既不