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AS-605240

Catalog No.: 160926007
Cas No.: 648450-29-7
Purity : 98% by HPLC 
160926007 - AS-605240 | CAS 648450-29-7

Catalog number : 160926007

CAS number : 648450-29-7

分子式 : C12H7N3O2S 

分子量 : 257.27 

Iupac 化学名称 : (E)-5-(quinoxalin-6-ylmethylene)thiazolidine-2,4-dione 

Smile : N1=CC=NC2=CC(=CC=C12)\C=C\1/C(NC(S1)=O)=O

InChiKey : SQWZFLMPDUSYGV-UXBLZVDNSA-N

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同义词AS 605240; AS605240; AS-605240. 
英文同义词AS 605240; AS605240; AS-605240. 
分子式C12H7N3O2S 
分子量257.27 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileN1=CC=NC2=CC(=CC=C12)\C=C\1/C(NC(S1)=O)=O
InChiKeySQWZFLMPDUSYGV-UXBLZVDNSA-N
InChiInChI=1S/C12H7N3O2S/c16-11-10(18-12(17)15-11)6-7-1-2-8-9(5-7)14-4-3-13-8/h1-6H,(H,15,16,17)/b10-6+
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Orally administration of AS605240 significantly prevented lung inflammation and reduced collagen deposition. AS605240 also inhibited augmented expression of TNF-alpha and IL-1beta induced by bleomycin instillation. AS605240 may be a useful in treating inflammation diseases. AS605240 may represent a promising novel agent for the future therapy of pulmonary fibrosis.  

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